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Patristic A.D. 604 · Historical Christian Faith commentaries database, on Isa 64:6 (Morals on the Book of Job, Book 9.38)

Gregory the Great, on Isa 64:6

Gregory the Great · c. A.D. 540–604
Isa 64:6 · Douay-Rheims
“And we are all become as one unclean, and all our justices as the rag of a menstruous woman: and we have all fallen as a leaf, and our iniquities, like the wind, have taken us away.”
On this verse:
“It is hence that Isaiah laments bitterly, saying, And we all do fade as a leaf; and our iniquities like the wind have taken us away. And there is none that calleth upon Thy Name, that stirreth up himself to take hold of Thee. Now any of the righteous may sometimes be able to resist the visitations of a present judgment, by the merits of a derived innocency, but they have no power by their own goodness to rid mankind of the woes of the death to come. Therefore let the holy man bethink himself whereunto the human race has run out, let him cast his eye on the woes of eternal death, which it is plain that human righteousness can never withstand, let him see how frowardly man has offended, let him see how severely the wrath of the Creator is directed against man, and let him call for the Mediator between God and man, God and Man in one, forasmuch as he beholds Him destined to come long after. ... For the Redeemer of Mankind, who was made the Mediator between God and Man through the flesh, because that He alone appeared righteous among men, and yet, even though without sin, was notwithstanding brought to the punishment of sin, did both convict man, that he might not sin, and withstand God, that He might not smite; He gave examples of innocency that He took upon Him the punishment due to wickedness.”
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