The interpretation timeline
Luke 4:38 Douay-Rheims

And Jesus rising up out of the synagogue, went into Simon’s house. And Simon’s wife’s mother was taken with a great fever, and they besought him for her.

A.D. 253 – 1849 8 witnesses 13 excerpts

Patristic

before A.D. 750
253
A.D.
Origen Patristic
c. A.D. 184–253
“Here Luke speaks figuratively, as of a command given to a sensible being, saying, that the fever was commanded, and neglected not the work of Him who commanded it. Hence it follows: And she arose, and ministered unto them.”
397
A.D.
Ambrose of Milan Patristic
A.D. 339–397
“Luke having first introduced a man delivered from an evil spirit, goes on to relate the healing of a woman. For our Lord had come to heal each sex, and he ought first to be healed who was first created. Hence it is said, And he arose out of the synagogue, and entered into Simon’s house.”
“But if we weigh these things with deeper thoughts, we shall consider the health of the mind as well as the body; that the mind which was assailed by the wiles of the devil may be released first. Eve was not a hungered before the serpent beguiled her, and therefore against the author of evil himself ought the medicine of salvation first to operate. Perhaps also in that woman as in a type our flesh languished under the various fevers of crimes, nor should I say that the fever of love was less than that of bodily heat.”
Source
407
A.D.
John Chrysostom Patristic
A.D. 347–407
“(Hom. 27. in Matt.) For He honoured His disciples by dwelling among them, and so making them the more zealous.”
“(ut sup.) Because Matthew is silent on the point of asking Him, he does not differ from Luke, or it matters not, for one Gospel had brevity in view, the other accurate research. It follows: And he stood over her, &c.”
“(ut sup.) For since the disease was curable, He shewed His power by the manner of the cure, doing what art could never do. For after the allaying of the fever, the patient needs much time ere he be restored to his former health, but at this time all took place at once.”
444
A.D.
A.D. 376–444
“Now see how Christ abides in the house of a poor man, suffering poverty of His own will for our sakes, that we might learn to visit the poor, and despise not the destitute and needy. It follows: And Simon’s wife’s mother was taken with a great fever: and they besought him for her.”
“Let us therefore receive Jesus. For when He has visited us, we carry Him in our heart and mind; He will then extinguish the flames of our unlicensed pleasures, and will make us whole, so that we minister unto Him, that is, do things well-pleasing to Him.”
735
A.D.
Bede the Venerable Patristic
c. A.D. 672–735
“At one time at the request of others, at another of his own accord, our Saviour cures the sick, shewing that He is far aloof from the passions of sinners, and ever grants the prayer of the faithful, and what they in themselves little understand He either makes intelligible, or forgives their not understanding it. As, Who understands his errors? Lord, cleanse me from my secret faults. (Ps. 19:12.)”
Source
“For if we say that a man released from the devil represents morally the mind cleansed from unclean thoughts, consequently a woman vexed by fever, but cured at our Lord’s command, represents the flesh controlled by the rules of continence in the fury of its own lust.”

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“And he stood over her,.... "At her head", as the Persic version reads: he inclined himself towards her, to see how she did, and to take her by the hand, and lift her up; and rebuked the fever. The Syriac and Persic versions read, "her fever", that which was upon her; and it left her, as Mark says, "immediately"; as soon as ever he had touched her hand, and rebuked the fever, and bid it be gone: and immediately she arose, and ministered unto them; See Gill on Mat 8:15.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“Simon's wife's mother - See on Mat 8:14-17 (note). As soon as Peter began to follow Christ, his family began to benefit by it. It is always profitable to contract an acquaintance with good men. One person full of faith and prayer may be the means of drawing down innumerable blessings on his family and acquaintance. Every person who knows the virtue and authority of Christ should earnestly seek his grace in behalf of all the spiritually diseased in his household; nor can he seek the aid of Christ in vain.”
Source
1849
A.D.
1774–1849
“It is evident that St. Peter was married; but after his call to the apostleship, he left his wife, as St. Jerome writes, in ep. xliii. Chap. ii. ad Julianum, and lib. i. adv. Jovin. See Matthew xix. 29.”
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.