The interpretation timeline

Rev 16:1

How this passage has been read — the sources, oldest to newest.

From the early Church Fathers to now.

Rev 16:1 · Douay-Rheims
“And I heard a great voice out of the temple, saying to the seven angels: Go, and pour out the seven vials of the wrath of God upon the earth.”
Patristic before A.D. 750
202
A.D.
Irenaeus Patristic
c. A.D. 130–202
“For the whole exodus of the people out of Egypt, which took place under divine guidance, was a type and image of the exodus of the Church which should take place from among the Gentiles; and for this cause He leads it out at last from this world into His own inheritance, which Moses the servant of God did not [bestow], but which Jesus the Son of God shall give for an inheritance. And if any one will devote a close attention to those things which are stated by the prophets with regard to the [time of the] end, and those which John the disciple of the Lord saw in the Apocalypse, he will find that the nations [are to] receive the same plagues universally, as Egypt then did particularly.”
Source
188 years pass — nothing from this stretch is hosted yet
390
A.D.
Ticonius Patristic
d. A.D. 390
“The inevitable outcome of the divine command is here revealed. However, also revealed is that authority which the church especially merited to receive by divine inspiration, namely, to inflict judgment upon those who are to be damned and to grant mercifully absolution to those who have changed their ways.”
247 years pass — nothing from this stretch is hosted yet
637
A.D.
Andreas of Caesarea Patristic
c. A.D. 563–637
“From this we are led to think that until the divine vexation with the wicked distinguishes who the righteous are, the saints in no wise obtain the lot of the Jerusalem above or the priesthood in the temple of God or the [final] rest. "It is necessary," it says, "that the plagues be completed." By way of the plagues the wages of sin are brought to light for those who are worthy to receive them, and these obtain the judicial sentence that has been determined for them. Then the habitation in the metropolis above will be awarded to the saints. I think that no one who considers each of the plagues in relation to those persons who are found at the consummation shall make an error concerning what is fitting and right. For being beneficent to humankind, God will determine that the unending torments in the coming age be lessened, but that in the present life the avenging scourges be brought upon those who deserve them, either through the prophets, Enoch and Elijah, or through the change of the elements or through the sufferings which occur from wars. Through such scourges there will be a moderation in the payment for sins. However, let us pray that we be chastised in a fatherly manner and not be scourged with harsh treatment by the wrath that comes from the Lord—"for there is no health in our flesh because of his anger"—so that having cleansed through the tears of repentance our robes which have been stained by sins, and being dressed as for a wedding, we might enter into the bridal chamber of Christ, our God, to whom belong all glory, honor and worship together with the Father and the Holy Spirit forever and ever. Amen.”
Source
735
A.D.
Bede Patristic
A.D. 673–735
“And I heard a great voice: Go and pour out the seven bowls, etc. The Church is given the power to impose judgment on the damned and to mercifully grant absolution to the converted. And indeed, all angels are commanded to pour out on the earth; but these earthly men receive different names due to the variety of their sins, so that just as the fullness of preaching and vengeance, so also the fullness of guilt is reckoned by the number seven.”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.