John Gill

When the wicked, even mine enemies and my foes, came upon me,.... They are wicked men, men of malignant spirits, and evildoers, who are the enemies and foes of the people of God, and who hate them with an implacable hatred, and do everything they can to distress and afflict them; and such enemies David had, who were many and mighty; and these "came upon" him, or "approached against" him (c), they drew near to him to make war with him, as the word signifies (d); they attacked him in an hostile manner; and their view was, as he says, to eat up my flesh, as they eat bread, Psa 14:4; to devour him at once, to make but one morsel of him, to destroy his life, to strip him of his substance, to take away his wives and children, as the Amalekites at Ziklag, Sa1 30:1; they stumbled and fell; the Lord put stumbling blocks in their way, and retarded their march, and hindered them from executing their designs; and they fell into the hands of David, and were subdued under him, or fell by death; and these past instances of divine goodness the psalmist calls to mind, to keep up his heart and courage, and animate and strengthen him against the fears of men, of death and hell. (c) "cum appropinquaverint adversum me", Pagninus; so Gejerus. (d) "Belligerantibus contra me", Junius & Tremellius; so Piscator & Ainsworth.