Tertullian

He likewise, when mentioning the cup and making the New Testament to be sealed "in his blood," affirms the reality of Christ's body. For no blood can belong to a body that is not a body of flesh. If any sort of body were presented to our view, which is not one of flesh, not being fleshly, it would not possess blood. In order, however, that you might discover how anciently wine is used as a figure for blood, turn to Isaiah, who asks, "Who is this that comes from Edom, from Bosor with garments dyed in red, so glorious in his apparel, in the greatness of his might? Why are your garments red, and your clothing as his who comes from the treading of the full winepress?" The prophetic Spirit contemplates the Lord as if he were already on his way to his passion, clad in his fleshly nature; and as he was to suffer therein, he represents the bleeding condition of his flesh under the metaphor of garments dyed in red, as if reddened in the treading and crushing process of the winepress, from which the laborers descend reddened with the wine juice, like men stained in blood.