Jamieson, Fausset & Brown

Concerning his Son Jesus Christ our Lord--the grand burden of this "Gospel of God." made of the seed of David--as, according to "the holy scriptures," He behooved to be. (See on Mat 1:1). according to the flesh--that is, in His human nature (compare Rom 9:5; Joh 1:14); implying, of course, that He had another nature, of which the apostle immediately proceeds to speak.