The interpretation timeline
Acts 28:25 Douay-Rheims

And when they agreed not among themselves, they departed, Paul speaking this one word: Well did the Holy Ghost speak to our fathers by Isaias the prophet,

A.D. 235 – 1871 5 witnesses 6 excerpts

Patristic

before A.D. 750
235
A.D.
Hippolytus of Rome Patristic
c. A.D. 170–235
“This is the Spirit that at the beginning "moved upon the thee of the waters; " by whom the world moves; by whom creation consists, and all things have life; who also wrought mightily in the prophets, and descended in flight upon Christ. This is the Spirit that was given to the apostles in the form of fiery tongues. This is the Spirit that David sought when he said, "Create in me a clean heart, O God, and renew a right spirit within me." Of this Spirit Gabriel also spoke to the Virgin, "The Holy Ghost shall come upon thee, and the power of the Highest shall overshadow thee." By this Spirit Peter spake that blessed word, "Thou art the Christ, the Son of the living God." By this Spirit the rock of the Church was stablished. This is the Spirit, the Comforter, that is sent because of thee, that He may show thee to be the Son of God.”
Source
407
A.D.
John Chrysostom Patristic
A.D. 347–407
“"Well said the Spirit:" as much as to say, It is not me that ye disbelieve. But God foreknew this from the first. "He discoursed," it says, "with boldness, unhindered": for it is possible to speak with boldness, yet hindered. His boldness nothing checked: but in fact he also spoke unhindered. "Well spake the Holy Ghost," etc. But this saying, "The Spirit said," is nothing wonderful: for an angel also is said to say what the Lord saith: but He the Spirit not so. When one is speaking of the things said by the angel, one does not say, Well said the angel, but, Well said the Lord. "Well said the Spirit:" as much as to say, It is not me that ye disbelieve. But God foreknew this from the first.”
Source
“"And when they agreed not among themselves, they departed, after that Paul had spoken one word, Well spake the Holy Ghost by Esaias the prophet unto our fathers, saying, Go unto this people, and say, Hearing ye shall hear, and shall not understand; and seeing ye shall see, and not perceive: for the heart of this people is waxed gross, and their ears are dull of hearing, and their eyes have they closed; lest they should see with their eyes, and hear with their ears, and understand with their heart, and should be converted, and I should heal them." But when they departed, as they were opposed to each other, then he reproaches them, not because he wished to reproach those that believed not, but to confirm these that believed. "Well said Esaias," says he to them. So that to the Gentiles it is given to know this mystery. No wonder then, if they did gainsay: this was foretold from the first.”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“And when they agreed not among themselves,.... One part believing what was said, and the other disbelieving; and such a division is the usual effect of the Gospel ministry; see Luk 12:51. Or this may be understood of the unbelieving party, who though they agreed in the main that Jesus was not the Messiah, yet might have different sentiments of the apostle; of the manner of his reasoning, and the nature of his proofs and arguments; and of some things which he delivered, which some might assent to, and others deny; as the Pharisees and Sadducees in the sanhedrim at Jerusalem disagreed about the doctrine of the resurrection: and the rather this may be thought to be the sense, because they not only departed, when very likely those that believed might stay longer, but because at their departure the apostle says something very cutting and stinging, and which he would not say in common of them all, of the believers; and besides, they are afterwards said to reason among themselves, Act 28:29. They departed; from the apostle's lodging to their own houses, or to some other place, where they could call over, and debate among themselves, the things they had heard: after that Paul had spoken one word; a very remarkable one, and full to the purpose, and which he gave them just at parting with them: well spake the Holy Ghost by Esaias the prophet unto our fathers; the passage referred to is in Isa 6:9, which the prophet Isaiah delivered under the influence and by the inspiration of the Holy Ghost, being moved by him, as all the holy men of God were; and which was very appropriate, not only to the Jewish fathers in the times of Isaiah, but to their posterity in succeeding ages, in the times of Christ and his apostles; see Mat 13:10; and were exceeding applicable to the present unbelieving Jews, who had been disputing with the apostle, and were now departing from him, in unbelief: and from hence it appears, that since it was the Holy Ghost that spake by Isaiah the prophet, and he that spoke to him and by him, was the Adon, Jehovah, and Lord of hosts, as is clear from Isa 6:1; it follows, that the Holy Ghost is a divine person, truly God, and equal with the Father and the Son.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“Agreed not among themselves - It seems that a controversy arose between the Jews themselves, in consequence of some believing, and others disbelieving; and the two parties contested together; and, in respect to the unbelieving party, the apostle quoted the following passage from Isa 6:9.”
1871
A.D.
1871
“when they--the Jews. agreed not among themselves--the discussion having passed into one between the two parties into which the visitors were now divided, respecting the arguments and conclusions of the apostle. they departed--the material of discussion being felt by both parties to be exhausted. after Paul had spoken one word--one solemn parting testimony, from those Scriptures regarded by both alike as "the Holy Ghost speaking" to Israel.”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.