The interpretation timeline
Genesis 21:18 Douay-Rheims

Arise, take up the boy, and hold him by the hand: for I will make him a great nation.

A.D. 407 – 1771 2 witnesses

Patristic

before A.D. 750
407
A.D.
John Chrysostom Patristic
A.D. 347–407
“What loving kindness on the Lord's part! Far from ignoring [Hagar] as a menial servant, he deigned to show her such wonderful concern for the reason that he had made the promise to the patriarch and the child was his. Hence the words "What is it, Hagar? Don't worry: God heard the cry of the child. Get up, pick him up, and take him by the hand; after all, I am to make him grow into a mighty nation." Don't lose heart, he is saying, at being driven from home. He will enjoy such providence at my hands as to become a mighty nation, even he.”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“And God opened her eyes, and she saw a well of water,.... Which she saw not before; not that she was really blind and had her eyes opened, or her sight restored, but they might be holden or restrained by the providence of God, that she should not see it before; or, through inattention and distraction of mind, might not observe it; or her eyes might be swelled with weeping and crying, that she saw it not; though it is not improbable that this well was not in being before, but was immediately produced by the power of God, who when he pleases can open mountains in the midst of the valleys, and make the wilderness a pool of water, Isa 41:18, the Jewish writers (k) say, it was created between the two evenings, that is, on the evening of the seventh day of the creation. Happy are those whose eyes are opened, by the Spirit and grace of God, to see the well of living water, the fountain and fulness of grace that is in Christ, where thirsty souls may come and drink and take their fill. And she went and filled the bottle with water, and gave the lad to drink; with which he was refreshed and recovered from his fainting, and was restored to health again. (k) Pirke Eliezer, ut supra. (c. 30.)”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.