The interpretation timeline
Genesis 3:19 Douay-Rheims

In the sweat of thy face shalt thou eat bread till thou return to the earth, out of which thou wast taken: for dust thou art, and into dust thou shalt return.

A.D. 45 – 1871 8 witnesses

Patristic

before A.D. 750
45
A.D.
c. 15 B.C.–A.D. 45
“XC. " And thou shalt eat the herb of the field ; in the sweat of thy brow shalt thou eat thy bread." He here speaks of the herb of the field and of bread, as if they were synonymous, or identical with one another. The herb of the field is the food of the irrational animal ; but the irrational animal is a worthless creature, which has been deprived of right reason. The outward senses are also irrational, though they are part of the soul. But the mind, which is eager for the attainment of those things which are the objects of the outward sense by means of the irrational outward senses, does not attain its desires without labour and sweat ; for the life of the foolish man is very full of distress and very burdensome, since he is always aiming at and greedily coveting the things which give pleasure, and all such things as wickedness is wont to do. And how long shall this last? " Until, " says God, "you return to the dust from which you were taken." For is he not now ranked among the things of the earth, and among things which have no consistency, ever since he deserted the wisdom which is from heaven ? We must consider therefore to what point he is coming back ; but may we not consider whether what he says has not some such meaning as this, that the foolish mind is at all times averted from right reason, and that it has been originally taken not from any sublime nature, but from some more earthly material, and whether it is stationary, OX THE CHERUBIM, ETC, 175 or whether it is in motion, it is always the same, and desirous of the same objects. On which account, God adds that, " Dust thou art, and unto dust shalt thou return." And this is equivalent to what has been said before. Moreover this sentence also signifies, the beginning and the end are one and the same thing. For there hadst thou beginning in the perishable bodies of the earth ; and again, thou shalt end in them, during the interval of your life, between its beginning and its end, passing along a road which is not plain and easy, but rough, full of briars and thorns, the nature of which is to tear and wound thee. A TREATISE ON THE CHERUBIM ; A.VD ON THE FTiAMTITO SWORD ; ON THE FIRST-BORN CHILD OF MAN, CAIN. PART I.”
Source
220
A.D.
Tertullian Patristic
c. A.D. 150–220
“We say, therefore, that the body falls to the ground by death, as indeed facts themselves show, in accordance with the law of God. For to the body it was said, ("Till you return to the ground, for out of it were you taken; for) dust you are, and unto dust shall you return." That, therefore, which came from the ground shall return to the ground. Now that falls down which returns to the ground; and that rises again which falls down. "Since by man came death, by man came also the resurrection." 1 Corinthians 15:21 Here in the word man, who consists of bodily substance, as we have often shown already. [Against Marcion 5.9] Now, although the clay is offensive (for its poorness), it is now something else. What I possess is flesh, not earth, even although of the flesh it is said: "Dust you are, and unto dust shall you return." In these words there is the mention of the origin, not a recalling of the substance. The privilege has been granted to the flesh to be nobler than its origin, and to have happiness aggrandized by the change wrought in it. Now, even gold is earth, because of the earth; but it remains earth no longer after it becomes gold, but is a far different substance, more splendid and more noble, though coming from a source which is comparatively faded and obscure. In like manner, it was quite allowable for God that He should clear the gold of our flesh from all the taints, as you deem them, of its native clay, by purging the original substance of its dross.[On the Resurrection of the Flesh 6]”
Source
430
A.D.
Augustine of Hippo Patristic
A.D. 354–430
“What shall we say about the judgment pronounced against the man? Are we perhaps to think that the rich, for whom the necessities of life come easily and who do not labor on the earth, have escaped this punishment? It says, "The earth will be cursed for you in all your works, and you shall eat from it in sadness and groaning all the days of your life. It will bring forth thorns and thistles for you, and you will eat the grain of your field. In the sweat of your brow you will eat your bread until you return to the earth from which you were taken, for you are earth, and you will return to the earth." It is certainly clear that no one escapes this sentence. For anyone born in this life has difficulty in discovering the truth because of the corruptible body. For as Solomon says, "The body that is corrupted weighs down the soul, and the earthly habitation presses down the mind that thinks many thoughts." These are the labors and sorrows that man has from the earth. The thorns and thistles are the prickings of torturous questions or thoughts concerned with providing for this life.”
Source

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
בזעת אפיך IN THE SWEAT OF THY FACE — after you have taken all this great trouble.”

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“In the sweat of thy face shalt thou eat bread,.... Or "of thy nose" (f), sweat appearing first and chiefly on the forehead, from whence it trickles down by the nose in persons employed in hard labour; and here it takes in all the labour used in cultivating the earth for the production of herbs, and particularly of corn, of which bread is made; with respect to which there are various operations in which men sweat, such as ploughing, sowing, reaping, threshing, winnowing, grinding, sifting, kneading, and baking; and it may have regard to all methods and means by which men get their bread, and not without sweat; and even such exercises as depend upon the brain are not excused from such an expense: so that every man, let him be in what station of life he will, is not exempt, more or less, from this sentence, and so continues till he dies, as is next expressed: till thou return unto the ground, his original, out of which he was made; that is, until he dies, and is interred in the earth, from whence he sprung; signifying that the life of man would be a life of toil and labour to the very end of it: and nothing else can man expect in it: for dust thou art, and unto dust shall thou return; his body was composed of the dust, was of the earth, earthly, and should be reduced to that again by death, which is not an annihilation of man, but a bringing him back to his original; which shows what a frail creature man is, what little reason he has to be proud of himself, when he reflects from whence he came and whither he must go; see Ecc 12:7. (f) "nasi tui", Picherellus.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“In the sweat of thy face - Though the whole body may be thrown into a profuse sweat, if hard labor be long continued, yet the face or forehead is the first part whence this sweat begins to issue; this is occasioned by the blood being strongly propelled to the brain, partly through stooping, but principally by the strong action of the muscles; in consequence of this the blood vessels about the head become turgid through the great flux of blood, the fibres are relaxed, the pores enlarged, and the sweat or serum poured out. Thus then the very commencement of every man's labor may put him in mind of his sin and its consequences. Dust thou art, and unto dust shalt thou return - God had said that in the day they ate of the forbidden fruit, dying they should die - they should then become mortal, and continue under the influence of a great variety of unfriendly agencies in the atmosphere and in themselves, from heats, colds, drought, and damps in the one, and morbid increased and decreased action in the solids and fluids of the other, till the spirit, finding its earthly house no longer tenable, should return to God who gave it; and the body, being decomposed, should be reduced to its primitive dust. It is evident from this that man would have been immortal had he never transgressed, and that this state of continual life and health depended on his obedience to his Maker. The tree of life, as we have already seen, was intended to be the means of continual preservation. For as no being but God can exist independently of any supporting agency, so man could not have continued to live without a particular supporting agent; and this supporting agent under God appears to have been the tree of life. Ολιγη δε κεισομεσθα Κονις, οστεων λυθεντων. Anac. Od. 4., v. 9. "We shall lie down as a small portion of dust, our bones being dissolved."”
Source
1849
A.D.
1774–1849
“Dust, as to the visible part; and thy soul created out of nothing. This might serve to correct that pride, by which Adam had fallen; and the same humbling truths are repeated to us by the Church every Ash-Wednesday, to guard us against the same contagion, the worm of pride, to which we are all so liable. Thus Adam was again assured that he should die the death, with which God had threatened him, and which the devil had told Eve would not be inflicted. (”
Source
1871
A.D.
1871
“till thou return unto the ground--Man became mortal; although he did not die the moment he ate the forbidden fruit, his body underwent a change, and that would lead to dissolution; the union subsisting between his soul and God having already been dissolved, he had become liable to all the miseries of this life and to the pains of hell for ever. What a mournful chapter this is in the history of man! It gives the only true account of the origin of all the physical and moral evils that are in the world; upholds the moral character of God; shows that man, made upright, fell from not being able to resist a slight temptation; and becoming guilty and miserable, plunged all his posterity into the same abyss (Rom 5:12). How astonishing the grace which at that moment gave promise of a Saviour and conferred on her who had the disgrace of introducing sin the future honor of introducing that Deliverer (Ti1 2:15).”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.