Jer 51:55

“And I will make drunk her princes,.... With the wine of divine wrath; that is, slay them; though there may be an allusion to their being drunk with wine at the feast Belshazzar made for his thousand lords; who are the princes here intended, together with the king and his royal family, Dan 5:1; and her wise men, her captains, and her rulers, and her mighty men: the counsellors of state, priests, magicians, and astrologers; officers in the army, superior and inferior ones; and the soldiers and warriors, whom Cyrus and his men slew; when they entered the city; compare with this Rev 19:18; and they shall sleep a perpetual sleep, and not awake; be all asleep in their drunken fits, and be slain therein; and so never wake, or live more. The Targum is, "and they shall die the second death, and not come into the world to come;'' See Gill on Jer 51:39; saith the king, whose name is the Lord of hosts; the King of kings and Lord of lords; the Lord of armies in heaven and earth; and can do, and does, what he pleases in both worlds.”

“great voice--Where once was the great din of a mighty city. there shall be the silence of death [VATABLUS]. Or, the "great voice" of the revellers (Jer 51:38-39; Isa 22:2). Or, the voice of mighty boasting [CALVIN], (compare Jer 51:53). her waves--"when" her calamities shall cause her to give forth a widely different "voice," even such a one as the waves give that lash the shores (Jer 51:42) [GROTIUS]. Or, "when" is connected thus: "the great voice" in her, when her "waves," &c. (compare Jer 51:13). CALVIN translates, "their waves," that is, the Medes bursting on her as impetuous waves; so Jer 51:42. But the parallel, "a great voice," belongs to her, therefore the wave-like "roar" of "their voice" ought also belong to her (compare Jer 51:54). The "great voice" of commercial din, boasting, and feasting, is "destroyed"; but in its stead there is the wave-like roar of her voice in her "destruction" (Jer 51:54).”