The interpretation timeline
Luke 11:50 Douay-Rheims

That the blood of all the prophets which was shed from the foundation of the world, may be required of this generation,

A.D. 373 – 1871 4 witnesses

Patristic

before A.D. 750
373
A.D.
c. A.D. 296–373
“(Apol. 1. de fuga sua.) Now if they kill, the death of the slain will cry out the louder against them; if they pursue, they send forth memorials of their iniquity, for flight makes the pursuit of the sufferers to redound to the great disgrace of the pursuers. For no one flees from the merciful and gentle, but rather from the cruel and evil-minded man. And therefore it follows, That the blood of all the prophets who have been slain from the foundation of the world may be required of this generation.”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“Woe unto you lawyers,.... Who are particularly addressed again in distinction from the Pharisees, though much the same things are said to them both in Mat 23:13 for ye have taken away the key of knowledge; of the Scriptures, of the law, and the prophets, and the true interpretation of them, and especially of such places as refer to the Messiah, and the Gospel dispensation, called the kingdom of heaven, Mat 23:13 they had not only arrogated the knowledge of these to themselves, setting up for the only interpreters of the sacred writings; but they had took away from the people the true knowledge and sense of them, by their false glosses upon them, so that they were destroyed for lack of knowledge: and hence came that famine of hearing the word, which they say (c) should be before the coming of the King Messiah, and now was. The Syriac and Arabic versions read, "the keys of knowledge"; and the Ethiopic version, "the key of righteousness". The Jews sometimes speak of "the keys of the law", and represent the oral law as the root and key of the written law (d): but, alas! it was by the oral law, or traditions of the elders, that they took away the key, or obscured the true sense of the written law. Some think, that here is an allusion to the custom of delivering a key to any one, when he was ordained or promoted to the dignity of a doctor: it is said of R. Samuel (e), that "when he died they put, "his key", and his writing book into his coffin, because he was not worthy of a son'' to succeed him: ye entered not in yourselves; into the kingdom of heaven, the Gospel dispensation, neither receiving doctrines, nor submitting to its ordinances: and them that were entering in ye hindered; by reproaching the miracles and ministry of Christ; by threatenings and excommunications; See Gill on Mat 23:13. (c) Targum in Ruth i, 1. (d) Zohar in Exod. fol. 46. 1. (e) Vid. Cameron. in loc.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“That the blood - That the particle ινα may be translated so that, pointing out the event only, not the design or intention, Bishop Pearce has well shown in his note on this place, where he refers to a like use of the word in Luk 9:45; Luk 14:10; Joh 10:17; Rom 5:20; Rom 11:11; Co1 1:15, Co1 1:31, etc.”
1871
A.D.
1871
“all . . . required of this generation--As it was only in the last generation of them that "the iniquity of the Amorites was full" (Gen 15:16), and then the abominations of ages were at once completely and awfully avenged, so the iniquity of Israel was allowed to accumulate from age to age till in that generation it came to the full, and the whole collected vengeance of Heaven broke at once over its devoted head. In the first French Revolution the same awful principle was exemplified, and Christendom has not done with it yet. prophets--in the New Testament sense (Mat 23:34; see Co1 12:28).”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.