The interpretation timeline
Exodus 20:7 Douay-Rheims

Thou shalt not take the name of the Lord thy God in vain: for the Lord will not hold him guiltless that shall take the name of the Lord his God in vain.

A.D. 339 – 1875 8 witnesses 9 excerpts

Patristic

before A.D. 750
339
A.D.
c. A.D. 260–339
“Here too the Lord himself teaches in the passage before us about another Lord. For he says, "I am the Lord thy God," and adds, "You shall not take the name of the Lord your God in vain." The second Lord is here mystically instructing his servant about the Father, that is to say, the God of the universe. And you could find many other similar instances occurring in Holy Scripture, in which God speaks as if in a second voice about another. The Lord himself speaks as if about another.”
Source
430
A.D.
Augustine of Hippo Patristic
A.D. 354–430
“The second commandment: "You shall not take the name of the Lord your God in vain; for whoever takes the name of the Lord his God in vain will not be purified." The name of the Lord our God Jesus Christ is Truth: he himself said, "I am the truth." So truth purifies; futility defiles. And because whoever speaks the truth speaks from what is God's—for "whoever speaks falsehood speaks from what is his own"—to speak the truth is to speak reasonably, whereas to speak futility is to make a noise rather than to speak. Rightly, because the second commandment means love of the truth, the opposite of that is love of futility.”
Source
“You are told "Do not take the name of the Lord your God in vain"; do not regard Christ as a creature because for your sake he put on the creature. And you, you despise him who is equal to the Father and one with the Father.”

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
לשוא IN VAIN — for no valid reason, idly. What is a שבועת שוא, an oath taken for no valid reason? If one takes an oath declaring something, the nature of which is evident, to be different from what it is: e. g., swearing about a stone pillar that it is of gold (Shevuot 29a).”
1270
A.D.
Ramban Jewish
1194–1270
“LO THISA’ (THOU SHALT NOT TAKE) THE NAME OF THE ETERNAL THY G-D IN VAIN. This verse has already been explained in the words of our Rabbis. He prohibits [here] swearing by the Glorious Name in vain, such as swearing that which is contrary to facts known to man, or swearing to [the truth of] a self-evident fact. For example: if one swears that a pillar of marble is of gold, or that it is of marble, and the pillar is right before them and they recognize it as such [that it is of marble]. By way of the plain meaning of Scripture, the verse also prohibits the taking of the Glorious Name in vain upon one’s lips [even without an oath], the usage of the term [lo thisa] being similar to these expressions: ‘Lo thisa’ (Thou shalt not utter) a false report; Nor ‘esa’ (do I take) their names upon my lips. Speaking is called thisa, [which literally means “lifting”], because the speaker thereby lifts up his voice. Similarly: ‘masa’ (The burden) of the word of the Eternal; also, In that day ‘yisa’ (shall he swear), saying: I will not be a healer, which means that he will lift up his voice to say so. And in truth, this — [i.e., just taking G-d’s Name in vain even without an oath] — is also forbidden, and in the language of the Sages, it is called “pronouncing the Name of Heaven to no purpose.” Thus our Rabbis have already said: 2. “Whence do we know that [in dedicating a beast for a sacrifice] a man should not say, ‘Unto the Eternal this is a whole-offering,’ or ‘Unto the Eternal this is a sin-offering,’ but instead he should say, ‘This is a whole-offering unto the Eternal,’ ‘This is a sin-offering unto the Eternal’? Scripture therefore says, an offering unto the Eternal. And must we not reason by using the method of kal vachomer?, Note 208. If the Torah said of him who is about to dedicate [something to Heaven], ‘Let My Name not rest on it until [he has first said] korban (sacrifice)’, is it not logical [that we must not pronounce the Name of Heaven to no purpose]!” He has placed this commandment after the prohibition of idolatry, because just as it is proper to fear the Great and Fearful Name by not giving His Glory to another, so it is fitting to give glory to His Name. He who takes it in vain profanes it, similar to that which is written, And ye shall not swear by My Name falsely, so that thou profane not the Name of thy G-d. Just as He was stringent in the case of idolatry and wrote the punishment [for transgression], i.e., that He is a jealous G-d, visiting the iniquity of the fathers upon the children, so did He record here the punishment that He will not hold him guiltless. He used this expression instead of saying that He will visit his sin upon him, [as He did in the case of idolatry], because people who swear [in vain] do not consider it a real sin, and they think it is proper that He forgive them. Therefore He said that whosoever toucheth that shall not go unpunished. Rabbi Abraham ibn Ezra has written appropriately on this verse. Now the language of this verse, the Name of the Eternal thy G-d, implies that it is as if Moses was speaking, and so also in the case of all the following commandments, whereas in the first two verses G-d is speaking: I; Who brought thee out; before Me; For I; Of them that love Me and keep My commandments. It is for this reason that our Rabbis of blessed memory have said: “We heard the two commandments — I am the Eternal thy G-d and Thou shalt have no other gods — from the Almighty Himself,” for they are the root of everything. But Rabbi Abraham ibn Ezra asked [concerning this tradition of the Rabbis] that Scripture says, And G-d spoke all these words, and still more clearly it is written [following the Ten Commandments], These words the Eternal spoke unto all your assembly, and again it is written there, And He wrote them down upon two Tablets of stone,, 4:13. meaning that as He said the Ten Commandments to all your assembly, so He wrote them down upon the Tablets! I will explain to you the tradition of our Rabbis [that we heard the first two commandments from the Almighty Himself]. Surely all Israel heard the entire Ten Commandments from the mouth of G-d, as the literal meaning of Scripture indicates. But in the first two commandments, they heard the utterance of speech and understood their words even as Moses understood them. Therefore He spoke to them directly [in the first person], just as a master speaks to his servant, as I have mentioned. From then on, in the rest of the commandments, they heard a voice of speech but they did not understand it, and it became necessary for Moses to explain to them each and every commandment until they understood it from Moses. And so [the Rabbis] explained:. In explanation thereof, the Sages said in the Mechilta that Moses brought to them every commandment as he heard it.” I have not been able to identify the exact quotation in the Mechilta. Moses spoke, and G-d answered him by a voice. Therefore [the rest of the Ten Commandments] were addressed by G-d to Moses so that he should tell them thus. The reason [that the first two commandments were spoken to the people directly by G-d] was so that they should all be prophets in the belief of G-d, [His existence, and His Unity], and in the prohibition of idolatry, as I have explained., 19:9. Those are the root of the whole Torah and the commandments, just as He said, Assemble Me the people, and I will make them hear My words, that they may learn to fear Me all the days. But in the rest of the Ten Commandments, they received their explanation from the mouth of Moses after having heard a voice of words,, Verse 12. while in all other commandments [of the whole Torah], they believed in Moses completely.”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“Thou shall not take the name of the Lord God in vain,.... Make use of the name Lord or God, or any other name and epithet of the divine Being, in a light and trifling way, without any show of reverence of him, and affection to him; whereas the name of God ought never to be mentioned but in a grave and serious manner, and with an awe of the greatness of his majesty upon the mind. The Targums of Onkelos and Jonathan restrain this to swearing by the name of the Lord; and so the Jewish writers generally interpret it either of swearing lightly, rashly, or falsely; and to this it may very well be extended, though not limited; and so forbids, as all profane oaths; imprecations, and curses by the name of God, which the mouths of wicked men are full of, so swearing by it in matters trivial, and of no importance; for swearing even by the name of the Lord ought not to be used but in matters of moment and consequence, for the confirmation of a thing, and putting an end to strife, and where a matter cannot be determined and decided without an appeal to God. And great care should be taken that a man swears to that which is true, and not false; for false swearing, or perjury, is a very grievous sin, and as it is strictly forbidden, it is severely punished by the Lord, as follows; see Lev 19:12, this is the third command, and the reason enforcing it follows: for the Lord will not hold him guiltless that taketh his name is vain; will not look upon him as an innocent person, and treat him as such; will not acquit and discharge him as just and righteous; but on the contrary will consider him as a guilty person, a profaner of his name, and a transgressor of his law, and will condemn and punish him, if not in this world, yet in the world to come; and so the Targum of Jonathan, by way of explanation, adds,"in the day of the great judgment;''see Mal 3:5.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“Thou shalt not take the name of the Lord thy God in vain - This precept not only forbids all false oaths, but all common swearing where the name of God is used, or where he is appealed to as a witness of the truth. It also necessarily forbids all light and irreverent mention of God, or any of his attributes; and this the original word לשוא lashshav particularly imports: and we may safely add to all these, that every prayer, ejaculation, etc., that is not accompanied with deep reverence and the genuine spirit of piety, is here condemned also. In how many thousands of instances is this commandment broken in the prayers, whether read or extempore, of inconsiderate, bold, and presumptuous worshippers! And how few are there who do not break it, both in their public and private devotions! How low is piety when we are obliged in order to escape damnation, to pray to God to "pardon the sins of our holy things!" Even heathens thought that the names of their gods should be treated with reverence. Παντως μεν δη καλον επι ηδευμα, θεων ονοματα μη χραινειν ῥᾳδιως, εχοντα ὡς εχουσιν ἡμων ἑκαστοτε τα πολλα οἱ πλειστοι καθαροτητος τε και ἁγνειας τα περι τους θεους. "It is most undoubtedly right not easily to pollute the names of the gods, using them as we do common names; but to watch with purity and holiness all things belonging to the gods." The Lord will not hold him guiltless, etc. - Whatever the person himself may think or hope, however he may plead in his own behalf, and say he intends no evil, etc.; if he in any of the above ways, or in any other way, takes the name of God in vain, God will not hold him guiltless - he will account him guilty and punish him for it. Is it necessary to say to any truly spiritual mind, that all such interjections as O God! my God! good God! good Heavens! etc., etc., are formal positive breaches of this law? How many who pass for Christians are highly criminal here!”
Source
1849
A.D.
1774–1849
“In vain. On trifling occasions, rashly, or falsely. “Those who swear often, diminish their credit among the wise.” (Philo)”
1875
A.D.
Keil & Delitzsch Lutheran
1861–1875
“The Third Word, "Thou shalt not take the name of Jehovah thy God in vain," is closely connected with the former two. Although there is no God beside Jehovah, the absolute One, and His divine essence cannot be seen or conceived of under any form, He had made known the glory of His nature in His name (Exo 3:14., Exo 6:2), and this was not to be abused by His people. שׁם נשׁא does not mean to utter the name (נשׁא never has this meaning), but in all the passages in which it has been so rendered it retains its proper meaning, "to take up, life up, raise;" e.g., to take up or raise (begin) a proverb (Num 23:7; Job 27:1), to lift up a song (Psa 81:3), or a prayer (Isa 37:4). And it is evident from the parallel in Psa 24:4, "to lift up his soul to vanity," that it does not mean "to utter" here. שׁוא does not signify a lie (שׁקר), but according to its etymon שׁאה, to be waste, it denotes that which is waste and disorder, hence that which is empty, vain, and nugatory, for which there is no occasion. The word prohibits all employment of the name of God for vain and unworthy objects, and includes not only false swearing, which is condemned in Lev 19:12 as a profanation of the name of Jehovah, but trivial swearing in the ordinary intercourse of life, and every use of the name of God in the service of untruth and lying, for imprecation, witchcraft, or conjuring; whereas the true employment of the name of God is confined to "invocation, prayer, praise, and thanksgiving," which proceeds from a pure, believing heart. The natural heart is very liable to transgress this command, and therefore it is solemnly enforced by the threat, "for Jehovah will not hold him guiltless" (leave him unpunished), etc.”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.