The interpretation timeline
Genesis 28:12 Douay-Rheims

And he saw in his sleep a ladder standing upon the earth, and the top thereof touching heaven: the angels also of God ascending and descending by it;

A.D. 346 – 1871 11 witnesses

Patristic

before A.D. 750
346
A.D.
c. A.D. 270–346
“Our father Jacob too prayed at Bethel and saw the gate of heaven opened, with a ladder going up on high. This is a symbol of our Savior that Jacob saw; the gate of heaven is Christ, in accordance with what he said, "I am the gate of life; every one who enters by me shall live for ever." David too said, "This is the gate of the Lord, by which the righteous enter." Again, the ladder that Jacob saw is a symbol of our Savior, in that by means of him the just ascend from the lower to the upper realm. The ladder is also a symbol of our Savior's cross, which was raised up like a ladder, with the Lord standing above it.”
Source
430
A.D.
Augustine of Hippo Patristic
A.D. 354–430
“But what did he see that time on the ladder? Angels ascending and descending. So also is the church, brothers; the angels of God, good preachers, preaching Christ; that is, they ascend and descend upon the Son of man. How do they ascend, and how do they descend? From one we have an example. Hear the apostle Paul; what we find in him, let us believe also about the rest of the preachers of truth. See Paul ascending: "I know a man in Christ who fourteen years ago (whether in the body or out of the body I do not know, God knows) was caught up to the third heaven, and heard unutterable words which it is not granted to man to speak." You heard him ascending; hear him descending: "I could not speak to you as spiritual men but only as carnal, as to little ones in Christ. I gave you milk to drink, not solid food." Look, he who had ascended descended. Seek where he had ascended: "Up to the third heaven." Seek where he had descended: "I became a little one," he says, "in your midst, as if a nurse were fondling her own children."”
Source
523
A.D.
c. A.D. 450–523
“Now the Dweller in heaven shewed this ladder aforetime, as in a mystery, to the elect of the Fathers, the blessed Jacob; and also that those who went up and those who came down upon it were angels. And that that ladder belongeth not to heavenly angels alone, the word of the Book indicateth to us, because the angels of God were going up and coming down thereupon; for every man who draweth nigh to enquire thereat, and who beginneth to mount it, laboureth after the order of angels, and is numbered among the elect of spiritual beings, and he hath inscribed his name as a heavenly soldier. And as the children of men who receive human positions, and who labour in some one of the grades of the world, change the name of "rustics", by which they were formerly called, to "servants" (or soldiers), so also the man who of his own freewill enrolleth himself in the company which Christ hath formed, and who serveth in the army of spiritual beings, the word of the Book nameth him "angel", and not "man", and rightly so, because he hath begun the service of angels, and he is bound to receive their name. And he is called "angel" instead of "man" because of his service and manner of life, and not because of his nature. And moreover upon the ladder, Jacob the upright saw angels ascending and descending; those who were ascending were men, because it belongeth unto men to ascend from earth to heaven, and those who were descending were angels, because their country is heaven, and they descend from their country, the heights above, to the earth. Now therefore angels and the children of men were mingled upon that ladder that the Holy Book might teach us that a fair life is common both to spiritual and corporeal beings, and that the keeping of the commandments is obligatory to both of them. And the children of men keep the commandments when they are exalted from the depth to the height by the steps of the commandments, and the angels minister unto the wishes of [the Divine] Majesty when they are sent below from above. For those who are to inherit life, that is to say, those who are of the body in their nature and are inferior beings, the service of the commandments maketh celestial and spiritual beings; and the command of the Creator urgeth those who are celestial and spiritual by creation to go down to the country of terrestrial beings, and to abide continually with corporeal beings, so that from races which are different from each other, one Church may be gathered together in the bond of love, which will sing the services of God's will, and which will be wholly and entirely moved by one living and spiritual motion, even as the natural body is moved entirely by the life of the soul.”
Source

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
עלים וירדים ASCENDING AND DESCENDING — It states first ascending and afterwards descending! Those angels who accompanied him in the land of Israel were not permitted to leave the Land: they ascended to Heaven and angels which were to minister outside the Land descended to accompany him (Genesis Rabbah 68:12).”
1167
A.D.
Ibn Ezra Jewish
1089–1167
“The nature of a ladder [sulam] is a symbol [semel], or it is an explanation of the Gematria valuation of 'Sinai' (Genesis Rabbah 68:12-14). And Rabbi Shlomo HaSefardi said that 'ladder' hints at the highest soul and 'G-d's angels' hints at wise thoughts. Rabbi Joshua said that the reason for the ladder is that his (Jacob's) prayer rose on it and his salvation from the heavens came down on it. These explanations do not explain it in light of the prophecy of Zecharia (1:8), Amos (7:1), and Jeremiah (1:11). The reason for the ladder here is a metaphor, for nothing is concealed from G-d. Worldly things hang onto the heavens as though there is a ladder between them, upon which the angels go up to report on things after they have been walking along the earth. Likewise, it is written that other angels descend to fulfill G-d's tasks, like a king with his servants.”
Source
1270
A.D.
Ramban Jewish
1194–1270
“AND BEHOLD A LADDER SET UP ON THE EARTH AND THE TOP OF IT REACHED TO HEAVEN; AND BEHOLD THE ANGELS OF G-D ASCENDING AND DESCENDING ON IT. In a prophetic dream, He showed Jacob that whatever is done on earth is effected by means of the angels, and everything is by decree given to them by the Supreme One. The angels of G-d, whom the Eternal hath sent to walk to and fro through the earth, would not do anything minor or major until they return to present themselves before the Master of the whole earth, saying before Him, “We have traversed the earth,, Verse 11. and behold it dwells in peace, or is steeped in war and blood,” and He commands them to return, to descend to the earth and fulfill His charge. And He further showed him [Jacob] that He, blessed be He, stands above the ladder, and promises Jacob with supreme assurance to inform him that he will not be under the power of the angels, but he will be G-d’s portion, and that He will be with him always, as He said, And, behold, I am with thee, and will keep thee wherever thou goest for his [Jacob’s] excellence is superior to that of the other righteous ones of whom it is said, For He will give His angels charge over thee, to keep thee in all thy ways. And in the opinion of Rabbi Eliezer the Great this vision was akin to the one seen by Abram at the time of the covenant “between the parts” for He also showed Jacob the dominion of the Four Kingdoms,. Jacob, like Abraham, was thus shown the events that will happen to his descendants during all the generations of their exiles. their ascent and descent. This is the meaning of angels of G-d (mentioned here), just as it is said in the visions of Daniel: the prince of the kingdom of Greece, and the prince of the kingdom of Persia., Verse 13. Similarly, the angels mentioned in the verse before us are to be understood as the representatives of the various nations. And He promised him that He, exalted be He, will be with him wherever he will go among the nations, and He will guard him and rescue him from them. Thus the Rabbis have said: “The Holy One, blessed be He, showed him the Four Kingdoms, their dominion and their destruction. He showed him the prince of the kingdom of Babylon ascending seventy rungs and then descending the ladder. Then He showed him the prince of the kingdom of Media ascending one hundred and eighty rungs and then descending. And then He showed him the prince of the kingdom of Edom ascending and not coming down. Jacob then said to the prince of Edom, Yet thou shalt be brought down to the nether-world. The Holy One, blessed be He, said to [the prince of Edom], Though thou make thy nest as high as the eagle, etc.”.”
Source

Reformation

c. 1500 – 1650
1550
A.D.
Sforno Jewish
c. 1475–1550
“AND HERE, DIVINE ANGELS AND HERE, DIVINE ANGENS WERE GOING UP AND DOWN ON IT. For indeed, this is how it will be in the end, that the guardian spirits of the nations, after their rise, will fall, and God, may He be blessed, Who stands (v. 13) forever, will not forsake His people, as it says (Jer. 46:28), "I will make an end of all the nations ... But I will not make an end of you." WERE GOING UP AND DOWN ON IT. For indeed, this is how it will be in the end, that the guardian spirits of the nations, after their rise, will fall, and God, may He be blessed, Who stands (v. 13) forever, will not forsake His people, as it says (Jer. 46:28), "I will make an end of all the nations ... But I will not make an end of you."”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“And he dreamed,.... As he slept; not a common dream, but under divine direction and influence: and, behold, a ladder set upon the earth, and the top of it reached to heaven: denoting either the providence of God, and the various steps of it, bringing about his own glory and the good of his people; and which is steady, firm, and sure, and reaches to all things here on earth; and in an especial manner is concerned about the people of God, their protection and safety; and is directed and governed according to the will, counsels, and purposes of God in heaven; a view of which must be very encouraging to Jacob in his present circumstances: or else the incarnation and mediation of Christ, who in his human nature was to be in the fulness of time on earth, there to live a while, obey, suffer, and die, and so was the ladder set on earth; and his divine nature was the top of it, which reached heaven; here he was in that nature before his incarnation, and from hence he came; and indeed here he was in that when on earth; and as man, he ascended on high when he had done his work, and is now higher than the heavens; he may be fitly represented hereby as the Mediator, who has reconciled things in heaven and things on earth, and has as it were joined and united heaven and earth together: and the various rungs in this ladder, so considered, are Christ's interposition as a surety front eternity; his incarnation in time; his being under the law, and his obedience to it; his sufferings, the shedding of his blood, and the death of the cross; his resurrection from the dead, ascension to heaven, session at the right hand of God, and intercession there. Moreover this may point out to us Christ as the way to his Father, of access unto him, and acceptance with him, by which he communicates the blessings of his grace to men, and by which they ascend to God with their prayers and praises to him: as also as being the way to heaven and eternal happiness; the various steps to which are election in him, redemption by him, regeneration by his Spirit and grace, the several graces of his Spirit, faith, hope, and love, justification by his righteousness, pardon by his blood, adoption through him, and the resurrection of the dead: and, behold, the angels of God ascending and descending on it: which may be expressive of the employment of angels in the affairs of Providence, who receive their commission from heaven, and execute it on earth, in which they are diligent, faithful, and constant; and of the ministry of them, both to Christ personal, and to his church and people, even to every particular believer; see Joh 1:51.”
Source
1832
A.D.
Adam Clarke Methodist
1762–1832
“He dreamed, and behold a ladder - A multitude of fanciful things have been spoken of Jacob's vision of the ladder, and its signification. It might have several designs, as God chooses to accomplish the greatest number of ends by the fewest and simplest means possible. 1. It is very likely that its primary design was to point out the providence of God, by which he watches over and regulates all terrestrial things; for nothing is left to merely natural causes; a heavenly agency pervades, actuates, and directs all. In his present circumstances it was highly necessary that Jacob should have a clear and distinct view of this subject, that he might be the better prepared to meet all occurrences with the conviction that all was working together for his good. 2. It might be intended also to point out the intercourse between heaven and earth, and the connection of both worlds by the means of angelic ministry. That this is fact we learn from many histories in the Old Testament; and it is a doctrine that is unequivocally taught in the New: Are they not all ministering spirits, sent forth to minister for them who shall be heirs of salvation? 3. It was probably a type of Christ, in whom both worlds meet, and in whom the Divine and human nature are conjoined. The Ladder was set up on the Earth, and the Top of it reached to Heaven; for God was manifested in the Flesh, and in him dwelt all the fullness of the Godhead bodily. Nothing could be a more expressive emblem of the incarnation and its effects; Jesus Christ is the grand connecting medium between heaven and earth, and between God and man. By him God comes down to man; through him man ascends to God. It appears that our Lord applies the vision in this way himself, first, In that remarkable speech to Nathanael, Hereafter ye shall see the heaven opened, and the angels of God ascending and descending on the Son of man, Joh 1:51. Secondly, in his speech to Thomas, Joh 14:6 : I am the Way, and the truth, and the life; no man cometh unto the Father but by me.”
Source
1849
A.D.
1774–1849
“A ladder and angels, &c. This mysterious vision tended to comfort the patriarch, with the assurance that God would now take him under his more particular protection, when he was destitute of human aid. (Haydock) — The angels ascending, foretold that his journey would be prosperous; and descending, shewed that he would return with safety. (Menochius) — Or rather, the ladder represented the Incarnation of Jesus Christ, born of so many patriarchs from Adam, who was created by God, to the blessed Virgin Mary. He is the way by which we must ascend, by observing the truth, till we obtain life eternal. (Haydock) — Mercy and truth are like the two sides; the virtues of Christ are signified by the steps. Angels descend to announce this joyful mystery to men; they ascend to convey the prayers and ardent desires of the ancient saints, to hasten their redemption. (Menochius) — Our Saviour seems to allude to this passage, John i. 51; xiv. 6. The Providence of God, watching over all things, appears here very conspicuous.”
Source
1871
A.D.
1871
“he dreamed . . . and behold a ladder--Some writers are of opinion that it was not a literal ladder that is meant, as it is impossible to conceive any imagery stranger and more unnatural than that of a ladder, whose base was on earth, while its top reached heaven, without having any thing on which to rest its upper extremity. They suppose that the little heap of stones, on which his head reclined for a pillow, being the miniature model of the object that appeared to his imagination, the latter was a gigantic mountain pile, whose sides, indented in the rock, gave it the appearance of a scaling ladder. There can be no doubt that this use of the original term was common among the early Hebrews; as JOSEPHUS, describing the town of Ptolemais (Acre), says it was bounded by a mountain, which, from its projecting sides, was called "the ladder," and the stairs that led down to the city are, in the original, termed a ladder (Neh 3:15) though they were only a flight of steps cut in the side of the rock. But whether the image presented to the mental eye of Jacob were a common ladder, or such a mountain pile as has been described, the design of this vision was to afford comfort, encouragement, and confidence to the lonely fugitive, both in his present circumstances and as to his future prospects. His thoughts during the day must have been painful--he would be his own self-accuser that he had brought exile and privation upon himself--and above all, that though he had obtained the forgiveness of his father, he had much reason to fear lest God might have forsaken him. Solitude affords time for reflection; and it was now that God began to bring Jacob under a course of religious instruction and training. To dispel his fears and allay the inward tumult of his mind, nothing was better fitted than the vision of the gigantic ladder, which reached from himself to heaven, and on which the angels were continually ascending and descending from God Himself on their benevolent errands (Joh 1:51).”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.