The interpretation timeline
Isaiah 53:3 Douay-Rheims

Despised, and the most abject of men, a man of sorrows, and acquainted with infirmity: and his look was as it were hidden and despised, whereupon we esteemed him not.

A.D. 99 – 1875 10 witnesses

Patristic

before A.D. 750
99
A.D.
Clement of Rome Patristic
d. A.D. 99
“For Christ is of those who are humble-minded, and not of those who exalt themselves over His flock. Our Lord Jesus Christ, the Sceptre of the majesty of God, did not come in the pomp of pride or arrogance, although He might have done so, but in a lowly condition, as the Holy Spirit had declared regarding Him. For He says, "Lord, who has believed our report, and to whom is the arm of the Lord revealed? We have declared [our message] in His presence: He is, as it were, a child, and like a root in thirsty ground; He has no form nor glory, yea, we saw Him, and He had no form nor comeliness; but His form was without eminence, yea, deficient in comparison with the [ordinary] form of men. He is a man exposed to stripes and suffering, and acquainted with the endurance of grief: for His countenance was turned away; He was despised, and not esteemed. He bears our iniquities, and is in sorrow for our sakes; yet we supposed that [on His own account] He was exposed to labour, and stripes, and affliction. But He was wounded for our transgressions, and bruised for our iniquities. The chastisement of our peace was upon Him, and by His stripes we were healed. All we, like sheep, have gone astray; [every] man has wandered in his own way; and the Lord has delivered Him up for our sins, while He in the midst of His sufferings opens not His mouth. He was brought as a sheep to the slaughter, and as a lamb before her shearer is dumb, so He opens not His mouth. In His humiliation His judgment was taken away; who shall declare His generation? For His life is taken from the earth. For the transgressions of my people was He brought down to death. And I will give the wicked for His sepulchre, and the rich for His death, because He did no iniquity, neither was guile found in His mouth. And the Lord is pleased to purify him by stripes. If you make an offering for sin, your soul shall see a long-lived seed. And the Lord is pleased to relieve Him of the affliction of His soul, to show Him light, and to form Him with understanding, to justify the Just One who ministers well to many; and He Himself shall carry their sins. On this account He shall inherit many, and shall divide the spoil of the strong; because His soul was delivered to death, and He was reckoned among the transgressors, and He bare the sins of many, and for their sins was He delivered." [Isaiah 53:1-12] And again He says, "I am a worm, and no man; a reproach of men, and despised of the people. All that see me have derided me; they have spoken with their lips; they have wagged their head, [saying] He hoped in God, let Him deliver Him, let Him save Him, since He delights in Him." [Psalm 22:6-8] You see, beloved, what is the example which has been given us; for if the Lord thus humbled Himself, what shall we do who have through Him come under the yoke of His grace?”
Source
373
A.D.
c. A.D. 296–373
“Nor is even his death passed over in silence: on the contrary, it is referred to in the divine Scriptures, even exceedingly clearly.… He suffers it not for his own sake but for the immortality and salvation of all, and the counsels of the Jews against him and the indignities offered him at their hands.… O marvel at the loving-kindness of the Word, that for our sakes he is dishonored, that we may be brought to honor.”
Source
430
A.D.
Augustine of Hippo Patristic
A.D. 354–430
“Christ's deformity is what gives form to you. If he had been unwilling to be deformed, you would never have got back the form you lost. So he hung on the cross, deformed; but his deformity was our beauty.”

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
“Despised and rejected by men was he. So is the custom of this prophet: he mentions all Israel as one man, e.g., (44:2), “Fear not, My servant Jacob”; (44:1) “And now, hearken, Jacob, My servant.” Here too (52:13), “Behold My servant shall prosper,” he said concerning the house of Jacob. יַשְׂכִּיל is an expression of prosperity. Comp. (I Sam. 18:14) “And David was successful (מַשְׂכִּיל) in all his ways.” and as one who hides his face from us Because of their intense shame and humility, they were as one who hides his face from us, with their faces bound up in concealment, in order that we not see them, like a plagued man who hides his face and is afraid to look.”
Source
1167
A.D.
Ibn Ezra Jewish
1089–1167
וחדל אישים He ceased to be counted with men. איש מכאבות A man of sorrows. The servant of the Lord, or the whole nation of the Israelites; in the latter case איש is to be compared with the same word in the phrase יי איש מלחמה (Exod. 15:3), and to be explained a being; it is in the construct state. Sorrows, grief. The troubles which Israel has to suffer during the exile are meant. And we hid, as it were, our faces from him. Even in our days there are people who turn aside at the sight of a Jew, lest they may be obliged to assist him.”
Source
1256
A.D.
Thomas Aquinas Catholic
1225–1274
“Who has believed? Here he begins to set down remedies against the obstacles spoken of: and first, against sin, he promises the passion of Christ; second, against dejection, he promises exaltation, chapter 54: Give praise, thou barren; third, against poverty, he promises the free enjoyment of things, (chapter 55), All you that thirst. On the first point, two things. First he shows the loftiness of the mystery, because it is not easily believed even by report. By report — of those things which we have heard from you concerning Christ. (Abdias): We have heard a report, etc.; Habacuc 3: Lord, I have heard your hearing, and I feared. Nor is it easily seen — and the arm, that is, the Son of God, the power of God. Job 40: If you have an arm like God. Second, he pursues the order of what came to pass: and first, setting forth a likeness as to his exaltation: and he shall ascend — being born from his mother's womb, rising again from death, ascending from the world into heaven, and into the faith of the nations — like a young shoot, which grows upward and multiplies broadly. Above, 11: There shall come forth a rod out of the root of Jesse, and a flower shall rise out of his root. And as to his humanity: and as a root out of thirsty ground — that is, out of ground without moisture, which by reason of its dryness appears unlovely; so too he himself was born of his mother without male moisture. Apocalypse, last chapter: I am the root of David. Second, he sets down the exposition of the likeness: there is not. And first as to his humiliation; second as to his exaltation, from anguish. On the first, two things. First he describes Christ's humility; second, the meekness of the humbled one, he was offered. On the first, three things. First he describes the office of humility; second, the contempt of the humbled one, and as it were hidden; third, the fruit of the humiliation, but he was wounded. On the first, two things. First his humility is shown as to the concealment of his majesty: there is not to him beauty — as to the abundance of interior goods — nor comeliness — as to the abundance of exterior goods: for beauty properly regards loveliness as to the proportion of the members, but comeliness regards the fittingness of color and of the other things surrounding it. He had, indeed, beauty, for he was beautiful in form beyond the sons of men (Psalm 44); but it lay hidden on account of the weakness he had assumed. He had comeliness, for strength and comeliness are his clothing, Proverbs, last chapter; but it lay hidden on account of the poverty he kept. Whence Canticles 2: Let your voice sound in my ears. And therefore we — who were then unbelieving and afterward converted, in whose person he speaks — saw him, bodily, and there was no — magnificent — appearance, according to what is said, that the beauty of Priam was worthy of empire. Second, his humility is shown as to the manifestation of weakness: and we desired him, awaiting him with desire as a great redeemer. Aggeus 2: Behold, the desired of all nations shall come. And in dignity, against which we saw him despised, inglorious, the most abject of men, on account of the most shameful kind of death. Wisdom 2: Let us condemn him to a most shameful death. Proverbs 30: I am the most foolish of men. Great also in prosperity; against which we find him a man of sorrows, as it were wretched, full of sorrows. Lamentations 1: O all you who pass by the way, attend and see if there is sorrow like my sorrow. Great also in power; against which we find him knowing infirmity, by experience. 2 Corinthians, last chapter: For though he was crucified through weakness, yet he lives by the power of God. And as it were hidden. Here he shows the contempt of the humbled one: and first as to the majesty concealed in the withdrawal of honor, as it were hidden — majesty lying concealed beneath the weakness of the flesh. Whence we esteemed him not — not paying him the honor due. Above, 45: Truly you are a hidden God. Second, as to the weakness displayed, setting down the sign of that weakness: truly — as a true man — infirmities: weaknesses, such as hunger and thirst, he bore, he sustained; sorrows, sensible ones, in the passion; and sadness — or, taking infirmities as sins — he took away from us, or, in our place, he sustained the punishments. 1 Peter 2: He bore our sins upon the wood. Setting down also the contempt: and we esteemed him as it were a leper, unclean and a sinner, and therefore struck by God — for his own sins, as to the punishments — and humbled, as to the disgraces. Job 22: For your very great malice, and your infinite iniquities. And 39: They abhor, etc. Note on that word: And to whom is the arm of the Lord revealed? — that Christ is the arm, first, for scourging the demons. Psalm 88: With the arm of your strength you have scattered your enemies. Second, for supporting the weak. Above, 40: In his arm he will lift up the lambs. Third, for defending the faithful. Wisdom 5: His right hand shall rule them. Likewise on that word, young shoot — that Christ is the rod, first, for striking. Numbers 24: A star shall rise out of Jacob, and a rod shall spring up from Israel; second, for sustaining. Psalm 22: Your rod and your staff, they have comforted me. Third, for directing. Psalm 44: The rod of your direction. Likewise on that word, a root out of the ground — that Christ is the root, first, on account of its being hidden. Ecclesiasticus 1: To whom has the root of wisdom been revealed? Second, on account of the ministering of nourishment. Jeremias 17: He shall be like a tree that sends out its roots toward moisture. Third, on account of the sustaining of the whole tree. Romans 11: You do not carry the root. But he was wounded. Here he sets down the fruit of the humiliation, or of the passion: and first he assigns the moving reason: but he, not as we thought, was wounded — with thorns, nails, the lance — for our iniquities, to be taken away. Bruised — with scourges and blows. Or, wounded, as to what is said, struck; bruised, as to what is said, humbled. Lamentations 4: The spirit of our mouth, Christ the Lord. Second, he shows the benefit that follows, in the reconciliation of peace: the chastisement of peace — that is, he himself, for us, sustained the chastisement of correction; through which peace we have access to God. Romans 5: For if, when we were enemies, we were reconciled to God through the death of his Son; and in the restoration of lost health, by his bruise, which he had from the rods. 1 Peter 2: By whose bruise you were healed. Psalm 102: Who is propitious to all your iniquities, who heals all your infirmities. Third, he shows the necessity impending on our part, because all were infirm: whence all need a physician, and no other could supply a sufficient remedy. Romans 3: For there is no distinction between the Jew and the Greek: for all have sinned, and need penance. All we like sheep — 1 Peter 2: You were once as sheep not having a shepherd. He was offered. Here he shows the meekness of the sufferer; and first he sets forth this meekness itself, and first as to his voluntary offering of himself: he was offered — to God the Father, for us, as a victim; Psalm 53: I will freely sacrifice to you. Second, as to his patient suffering: and he opened not his mouth — as one contradicting and contending: even before Herod he answered nothing, Luke 23. Lamentations 4: Out of the mouth of the Most High, etc. Second, he sets down a likeness: as a sheep to the slaughter — because he was killed without resistance — and as a lamb, suffering injury without contradiction. Jeremias 11: I am as a lamb that is carried to be a victim. Note on that word, the most abject — that Christ was the most abject, first on account of the bitterness of his sorrow. Lamentations 1: O all you who pass by the way, attend and see if there is sorrow like my sorrow. Second, on account of the shamefulness of his death. Wisdom 2: Let us condemn him to a most shameful death. Third, on account of the greatness of the crime laid upon him. Proverbs 30: I am the most foolish of men, and the wisdom of men is not with me. Likewise on that word, a man of sorrows — that Christ was full of sorrows, first on account of the necessity of the malady. Above, 1: From the sole of the foot even to the crown there is no soundness in it. Second, on account of the outpouring of graces. John 1: Of his fullness we have all received grace. Third, on account of our obligation. 2 Corinthians 5: For this Christ has died, etc. From anguish. Having set down the humility of the passion, here he begins to set forth the glory of the exaltation, which is the reward of the passion, as is said, Philippians 2: For which cause God has exalted him. And first as to the escaping of dangers; second as to the vengeance upon his enemies, and he shall give the wicked; third as to the justification of men, if he shall lay down; fourth as to the victory over rebels, therefore will I distribute. On the first, two things. First he sets down the reward: from anguish — of the passion; from judgment — the unjust judgment by which he was judged by others — he was taken up, in the resurrection. Proverbs 11: The just man is delivered out of anguish. Second, he sets down the merit, setting forth the dignity of the sufferer, so that from the condition of the person the merit of the passion might be weighed: his generation — the eternal one, by which he is from the Father without a mother, or the temporal one, by which he is from a mother without a father — who? As it were no one, by natural reason, although in some measure by divine inspiration. Ecclesiasticus 43: Who has seen him, and shall declare? Setting down also the passion inflicted upon him: for he was cut off — by death, at the hands of the Jews — out of the land of the living — out of this life. Jeremias 12: Come, let us put wood into his bread, and root him out of the land of the living. Setting down also, on the part of God the Father, the acceptance of the passion: for the wickedness I struck — I permitted him to be struck. 1 Peter 3: Christ once for our sins, etc. And he shall give the wicked. Here he sets down the second point, namely the vengeance upon those who persecuted him: and first he sets down the reward: and he shall give the wicked — the Jews, into the hands of the Romans — for burial — because they had him guarded in the sepulcher. Proverbs 21: For the just shall be given, etc. Second, he sets down the merit as to the innocence of his life: because he did no iniquity — as to the sin of deed; in his mouth — as to the sin of the mouth. 1 Peter 2: Who did no sin, neither was guile found in his mouth. And as to his obedience unto death: and the Lord — the Father — willed. And he himself was obedient to the Father even unto death. Philippians 2: Become obedient unto death. 1 Corinthians 1: That which is weak of God is stronger than men. If he shall lay down. Here he sets down the third point, namely that through him the justification of men was accomplished: and first he sets down the reward against the sorrow of death, if he shall lay down — of his own will. John 10: I lay down my life. He shall see a long-lived seed — unto the end of the world, sons being regenerated for him by the power of his death. John 12: Unless the grain of wheat falling into the ground be dead, itself remains alone; but if it be dead, it brings forth much fruit. And the will shall be directed — shall be fulfilled — in his hand — in his work. 1 Thessalonians 4: This is the will of God, your sanctification. And against the labor of teaching: because he labored — in preaching and going about — he shall see — the nations converted to him — and shall be satisfied — as one having what he intends. John 4: I have food to eat which you know not. Second, he sets down the merit as to the exercise of preaching: by knowledge — that is, by teaching. Romans 5: Justified freely by faith. John 6: Lord, to whom shall we go? You have the words of eternal life. And as to the torment of death: iniquities — that is, the punishments for iniquities. Above, 46: I have made, I will bear. Therefore will I distribute. Here he sets down the fourth point, namely the victory over enemies: and first he sets down the subjection of the enemies: therefore will I distribute — as it were, I will give him his portion — the many — who shall believe in him — and he shall divide the spoils of the strong — that is, of those held captive by the demons — to his disciples, setting different ones over different nations. Osee 13: He shall snatch away the treasure of every desirable vessel. Psalm 67: The king of powers, of the beloved, beloved, and of the beauty of the house, to divide the spoils. Second, he sets down the reason of the subjection: as to death, because he delivered — and as to the kind of death, and with the wicked. Luke 23: And there were crucified with him two malefactors. Psalm 87: I am reckoned with them that go down into the pit. Third, the salvation of those subjected. For he did not subject them to himself as a tyrant, to torment them, but to save them. And he himself bore the sin of many — efficiently, though of all sufficiently — took it away, and prayed for the transgressors. Luke 23: Father, forgive them, for they know not what they do.”

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“He is despised, and rejected of men,.... Or, "ceaseth from men" (f); was not admitted into the company and conversation of men, especially of figure; or ceased from the class of men, in the opinion of others; he was not reckoned among men, was accounted a worm, and no man; or, if a man, yet not in his senses, a madman, nay, one that had a devil: or "deficient of men"; he had none about him of any rank or figure in life, only some few fishermen, and some women, and publicans, and harlots. The Vulgate Latin version renders it, "the last of men", the most abject and contemptible of mankind; despised, because of the meanness of his birth, and parentage, and education, and of his outward appearance in public life; because of his apostles and audience; because of his doctrines, not agreeably to carnal reason, and his works, some of them being done on the sabbath day, and, as they maliciously suggested, by the help of Satan; and especially because of his ignominious sufferings and death: a man of sorrows, and acquainted with grief: or "known by grief" (g); he was known by his troubles, notorious for them; these were his constant companions, his familiar acquaintance, with whom he was always conversant; his life was one continued series of sorrow, from the cradle to the cross; in his infancy his life was sought for by Herod, and he was obliged to be taken by his parents, and flee into Egypt; he ate his bread in sorrow, and with the sweat of his brow; he met with much sorrow from the hardness and unbelief of men's hearts, and from the contradiction of sinners against himself, and even much from the frowardness of his own disciples; much from the temptations of Satan, and more from the wrath and justice of God, as the surety of his people; he was exceeding sorrowful in the garden, when his sweat was as it were great drops of blood; and when on the cross, under the hidings of his Father's face, under a sense of divine displeasure for the sins of his people, and enduring the pains and agonies of a shameful and an accursed death; he was made up of sorrows, and grief was familiar to him. Some render it, "broken with infirmity", or "grief" (h): and we hid as it were our faces from him; as one loathsome and abominable as having an aversion to him, and abhorrence of him, as scorning to look at him, being unworthy of any notice. Some render it, "he hid as it were his face from us" (i); as conscious of his deformity and loathsomeness, and of his being a disagreeable object, as they said; but the former is best: he was despised, and we esteemed him not; which is repeated to show the great contempt cast upon him, and the disesteem he was had in by all sorts of persons; professors and profane, high and low, rich poor, rulers and common people, priests, Scribes, and Pharisees; no set or order of men had any value for him; and all this disgrace and dishonour he was to undergo, to repair the loss of honour the Lord sustained by the sin of man, whose surety Christ became. (f) "desiit viris", Montanus, Heb.; "desitus virorum", Piscator; "deficiens virorum", Cocceius; "destitutus viris", Vitringa. (g) "notus aegritudine", Montanus; "notus infirmitate," Cocceius. (h) "Attritus infirmitate"; so some in Vatablus, and R. Sol. Urbin. Ohel. Moed. fol. 96. 1. (i) "velut homo abscondens faciem a nobis", Junius & Tremellius; "et tanquam aliquis qui obtegit faciem a nobis", Piscator; "ut res tecta facie averanda prae nobis", Cocceius.”
Source
1849
A.D.
1774–1849
“Not. The whole life of Christ was spent in the midst of poverty, and contradictions, Hebrews iv. 15. He has thus taught us to despise ourselves.”
1871
A.D.
1871
“rejected--"forsaken of men" [GESENIUS]. "Most abject of men." Literally, "He who ceases from men," that is, is no longer regarded as a man [HENGSTENBERG]. (See on Isa 52:14; Isa 49:7). man of sorrows--that is, whose distinguishing characteristic was sorrows. acquainted with--familiar by constant contact with. grief--literally, "disease"; figuratively for all kinds of calamity (Jer 6:14); leprosy especially represented this, being a direct judgment from God. It is remarkable Jesus is not mentioned as having ever suffered under sickness. and we hid . . . faces--rather, as one who causes men to hide their faces from Him (in aversion) [MAURER]. Or, "He was as an hiding of the face before it," that is, as a thing before which a man covers his face in disgust [HENGSTENBERG]. Or, "as one before whom is the covering of the face"; before whom one covers the face in disgust [GESENIUS]. we--the prophet identifying himself with the Jews. See HORSLEY'S view (see on Isa 53:1). esteemed . . . not--negative contempt; the previous words express positive.”
Source
1875
A.D.
Keil & Delitzsch Lutheran
1861–1875
“On the contrary, the impression produced by His appearance was rather repulsive, and, to those who measured the great and noble by a merely worldly standard, contemptible. "He was despised and forsaken by men; a man of griefs, and well acquainted with disease; and like one from whom men hide their face: despised, and we esteemed Him not." All these different features are predicates of the erat that is latent in non species ei neque decor and non adspectus. Nibhzeh is introduced again palindromically at the close in Isaiah's peculiar style; consequently Martini's conjecture לא וגו נבזהוּ is to be rejected. This nibhzeh (cf., bâzōh, Isa 49:7) is the keynote of the description which looks back in this plaintive tone. The predicate chădal 'ı̄shı̄m is misunderstood by nearly all the commentators, inasmuch as they take אישׁים as synonymous with בני־אדם, whereas it is rather used in the sense of בני־אישׁ (lords), as distinguished from benē 'âdâm, or people generally (see Isa 2:9, Isa 2:11, Isa 2:17). The only other passages in which it occurs are Pro 8:4 and Psa 141:4; and in both instances it signifies persons of rank. Hence Cocceius explains it thus: "wanting in men, i.e., having no respectable men with Him, to support Him with their authority." It might also be understood as meaning the ending one among men, i.e., the one who takes the last place (S. ἐλάχιστος, Jer. novissimus); but in this case He Himself would be described as אישׁ, whereas it is absolutely affirmed that He had not the appearance or distinction of such an one. But the rendering deficiens (wanting) is quite correct; compare Job 19:14, "my kinsfolk have failed" (defecerunt, châdelū, cognati mei). The Arabic chadhalahu or chadhala ‛anhu (also points to the true meaning; and from this we have the derivatives châdhil, refusing assistance, leaving without help; and machdhûl, helpless, forsaken (see Lane's Arabic Lexicon). In Hebrew, châdal has not only the transitive meaning to discontinue or leave off a thing, but the intransitive, to case or be in want, so that chădal 'ı̄shı̄m may mean one in want of men of rank, i.e., finding no sympathy from such men. The chief men of His nation who towered above the multitude, the great men of this world, withdrew their hands from Him, drew back from Him: He had none of the men of any distinction at His side. Moreover, He was מכאבות אישׁ, a man of sorrow of heart in all its forms, i.e., a man whose chief distinction was, that His life was one of constant painful endurance. And He was also חלי ידוּע, that is to say, not one known through His sickness (according to Deu 1:13, Deu 1:15), which is hardly sufficient to express the genitive construction; nor an acquaintance of disease (S. γνωστὸς νόσῳ, familiaris morbo), which would be expressed by מידּע or מודע; but scitus morbi, i.e., one who was placed in a state to make the acquaintance of disease. The deponent passive ירוּע, acquainted (like bâtuăch, confisus; zâkbūr, mindful; peritus, pervaded, experienced), is supported by מדּוּע = מה־יּרוּע; Gr. τί μαθών. The meaning is not, that He had by nature a sickly body, falling out of one disease into another; but that the wrath instigated by sin, and the zeal of self-sacrifice (Psa 69:10), burnt like the fire of a fever in His soul and body, so that even if He had not died a violent death, He would have succumbed to the force of the powers of destruction that were innate in humanity in consequence of sin, and of His own self-consuming conflict with them. Moreover, He was kemastēr pânı̄m mimmennū. This cannot mean, "like one hiding his face from us," as Hengstenberg supposes (with an allusion to Lev 13:45); or, what is comparatively better, "like one causing the hiding of the face from him:" for although the feminine of the participle is written מסתּרת, and in the plural מסתּרים for מסתּירים is quite possible, we never meet with mastēr for mastı̄r, like hastēr for hastı̄r in the infinitive (Isa 29:15, cf., Deu 26:12). Hence mastēr must be a noun (of the form marbēts, marbēq, mashchēth); and the words mean either "like the hiding of the face on our part," or like one who met with this from us, or (what is more natural) like the hiding of the face before his presence (according to Isa 8:17; Isa 50:6; Isa 54:8; Isa 59:2, and many other passages), i.e., like one whose repulsive face it is impossible to endure, so that men turn away their face or cover it with their dress (compare Isa 50:6 with Job 30:10). And lastly, all the predicates are summed up in the expressive word nibhzeh: He was despised, and we did not think Him dear and worthy, but rather "esteemed Him not," or rather did not estimate Him at all, or as Luther expresses it, "estimated Him at nothing" (châshabh, to reckon, value, esteem, as in Isa 13:17; Isa 33:8; Mal 3:16). The second turn closes here. The preaching concerning His calling and His future was not believed; but the Man of sorrows was greatly despised among us.”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.