The interpretation timeline
Isaiah 66:3 Douay-Rheims

He that sacrificeth an ox, is as if he slew a man: he that killeth a sheep in sacrifice, as if he should brain a dog: he that offereth an oblation, as if he should offer swine’s blood; he that remembereth incense, as if he should bless an idol. All these things have they chosen in their ways, and their soul is delighted in their abominations.

A.D. 373 – 1871 8 witnesses 10 excerpts

Patristic

before A.D. 750
373
A.D.
c. A.D. 296–373
“He is angry with them, saying by Isaiah, "Who has required these of your hands?" And by Jeremiah, since they were very bold, he threatens, "Gather together your whole burnt offerings with your sacrifices, and eat flesh, for I did not speak to your ancestors or command them in the day that I brought them out of the land of Egypt, concerning whole burnt offerings and sacrifices." For they did not act as was right, neither was their zeal according to law, but they rather sought their own pleasure in such days, as the prophet accuses them, beating down their bondsmen and gathering themselves together for strifes and quarrels, and they struck the lowly with the fist and did all things that tended to their own gratification. For this cause, they continue without a feast until the end, although they make a display now of eating flesh, out of place and out of season. For, instead of the legally appointed lamb, they have learned to sacrifice to Baal; instead of the true unleavened bread, "they collect the wood, and their fathers kindle the fire, and their wives prepare the dough, that they make cakes to the host of heaven and pour out libations to strange gods, that they may provoke me to anger, says the Lord." … Therefore now, "he who among them sacrifices an ox is as he who strikes a man, and he who sacrifices a lamb is as he who kills a dog, he that offers fine flour, it is as [if he offered] swine's blood.…" Now these things will never please God, neither has the Word required this of them. But he says, "These have chosen their own ways, and their abominations are what their soul delights in."”
Source

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
“brings a gift of violence Heb. מְבָרֵךְ, blesses Me with a gift of violence, brings a gift of violence. This is its explanation, and the expression of בְּרָכָה applies to a gift that is for a reception. Comp. (Gen. 33: 11) “Please take my gift (בִּרְכָתִי).” Also (supra 36:16), “Make peace (בְרָכָה) with me and come out to me.” they, too, chose their ways They desire these evil ways, and I, too, will choose and desire their mockeries. Now if you ask the meaning of גַּם, too, so is the style of the Hebrew language to say twice גַּם one next to the other. Comp. (Deut. 32:25) “Both a young man and a virgin (גַּם בָּחוּר גַּם בְּתוּלָה)”; (I Kings 3:26) “neither mine nor yours (גַּם לִי גַּם לָךְ)”; (Ecc. 9:1) “neither love nor hate (גַּם אַהֲבָה גַּם שִׂנְאָה)”; (Num. 18:3) “and neither they nor you shall die (גַּם הֵם גַּם אַתֶּם).” Here, too, both they chose and I will choose.”
Source
1167
A.D.
Ibn Ezra Jewish
1089–1167
“He that killeth an ox, etc. I look to him that trembleth at my word, not to those that sacrifice burnt offerings, and at the same time act badly; for he that killeth an ox, מכה איש is as guilty as if he slew a man; it is considered as murder on his part, because the offering is not brought properly; or is guilty as if he struck a man, not killing, but hurting and wounding him; He that sacrificeth a lamb before me, is guilty, ערף כלב as if he killed a dog; עֹרֵף֭ with the accent on the last syllable is participle Kal of ערף to cut off the neck; comp. וערפו and they shall strike off the neck (Deut. 21:4); when it has the accent on the last syllable but one (עׁ֭רֶף neck) it is a noun; he that offereth an oblation is guilty דם חזיר as if he offered the swine’s blood; מזכיר לבונה he that burneth incense—comp. אזכרה incense (Lev. 2:2)—isguilty, מברך און as if he blessed iniquity. גם המה Even they, namely, your forefathers; the word אבותיכם is to be supplied. chosen, etc.”
Source
1256
A.D.
Thomas Aquinas Catholic
1225–1274
“Thus says the Lord. Here he determines the manner of the execution of the sentence already given: and first specifically as regards the Jews; second universally as regards all: but I, their works and thoughts. The first is divided into two: in the first he excludes false confidence; second he sets forth and determines the sentence given, as to the manner of its execution: Hear the word of the Lord. Concerning the first there are two parts. First he excludes false confidence in the holiness of the temple, showing that the temple is not the place of God: both from the greatness of God, who fills all things — whose seat heaven is called, because it shares abundantly in his goodness, just as a seat holds the greater part of the one sitting; while earth is his footstool, because the earth shares least in his goodness, just as the outermost part reaches only to the footstool — or by heaven the saints are meant, and by earth the earthly-minded. 3 Kings 8: if heaven and the heaven of heavens do not contain you. Jeremiah 23: I fill heaven and earth. Acts 17: not in the hand-made things of the temple. Then from rest: because each thing rests in the place that is its own place; but God does not rest in anything, rather all things rest in him, as made by him. And what is his place? Above, ch. 40: lift up on high. And he gives a useful remedy: but to whom — the poor one, that is, the humble man who considers himself small as to the present; the contrite, as to past sins; the trembling, as to his resolve concerning what is to be done in the future. Ecclesiasticus 15: his eyes are upon those who fear him. Second, he excludes the confidence they had conceived from the rite of sacrifices: and first he sets down their reprobation: he who sacrifices an ox — as if he were to say: their sacrifices are so abominable, as if they were doing something against the law, because they were offering the same things to idols. He who blesses — that is, praises and venerates. Above, ch. 1: do not offer sacrifice any more. Second, he shows the reason for the reprobation, first setting down their fault: they have chosen all these things — namely, the sacrifices — walking in their own ways, evil ones. Proverbs 2: they rejoice when they have done evil, and exult in the worst of things. Second, he threatens punishment: hence, and I — Proverbs 3: he himself will mock the mockers. Job 3: the fear that I feared has come upon me, and what I dreaded has happened to me. Third, he charges the sinners with hardness of heart: because I called — Proverbs 1: I called, and you refused. Hear the word of the Lord. Here he carries out the manner of executing the sentence already given: and first as to the rewards of the good; second as to the punishments of the wicked: and it shall be known. The first is in two parts. First he rouses attention: you who tremble, out of reverence for his words. Ecclesiasticus 2: you who fear the Lord, believe in him. Second, he pursues the promise: and first as to vengeance upon the mockers, setting down their mockery: your brothers have said. Let him be glorified — as if to say: let the glory of the Lord appear, which you expect — as if to say: it will never appear. Above, ch. 5: he will come quickly and swiftly, he will not fail nor grow weary in it. And foretelling their confusion: but they shall be confounded, in this way: a voice of the people, fearing; a voice of the Lord, as to the tumult of enemies. Zephaniah 1: the voice of the day of the Lord is bitter. Second, he carries out the promise as to the abundance of good things: and first as to the reuniting of the people, setting down the promise: before she was in labor — that is, suddenly, and at once, the children of Jerusalem shall be gathered to her, just as if a woman should suddenly bring forth a son, with no labor going before. Above, ch. 37: the children have come as far as the birth. Mystically it is expounded of the childbearing of the Blessed Virgin, and of the childbearing of the Church in the conversion of the faithful, and of the bringing-forth of the eternal generation. And he introduces a question of wonder: who has ever heard such things? Above, ch. 49: who has begotten for me? And he sets down the answer in the person of the Lord: shall not I myself bring forth? — gathering the Jews, or converting the faithful, or the Son from eternity. Similarly, Psalm 93: he who planted the ear, shall he not hear? Or he who formed the eye, does he not consider? And these arguments hold, if that which is of perfection in creatures is attributed to him, with everything that belongs to imperfection removed. Second, he promises immense consolation to those gathered. And first he invites others to rejoice with them: rejoice with Jerusalem — in her, as in the object of joy — setting down the condition of those who rejoice together, as to affection: you who love. Canticle of Canticles 5: eat, O friends, and drink, and be inebriated, dearest ones. As to the sign of affection: you who mourn. Matthew 5: blessed are they who mourn, for they shall be comforted. And the fruit of that shared rejoicing, as to the sharing of gladness, or of peace: that you may suck — Canticle of Canticles 1: your breasts are better than wine. As to the sharing of glory: that you may milk it out, as those who milk out milk. Job 22: then you shall abound in delights over the Almighty. Second, he promises a copious bestowal of peace: for thus says the Lord: I will turn — so that it may be called an overflow, like a river which, though it comes down with great force, does not overflow. And of glory, and as it were a torrent. Above, ch. 48: it would have been made like a river. Third, he promises the full reception of consolation. First as to the administering of the nations: which you shall suck — unto the glory of the nations, because the kings of the nations themselves shall comfort you, and shall sustain you. Hence there follows, at the breasts. Mystically he speaks of the apostles, who rejoiced in the glory of the nations swiftly converted, and carried them, as it were, to the breasts by gentle admonitions. Above, ch. 60: you shall suck milk. Second, as to the divine protection: as if to someone, a mother. Hebrews 12: you have forgotten the consolation. Third, as to the enjoyment of good things: you shall see — the good things given you by God; your bones — you who in adversity were like dry bones. Ezekiel 37: dry bones, hear the word of the Lord. Or, you shall see the divine essence. Ecclesiastes 11: light is sweet, and it is delightful for the eyes to see the sun. Bones, unto the resurrection. And it shall be known. Here he promises punishments to the wicked: and first he threatens punishment, setting down the indignation of the judge: the hand, afflicting the wicked among his servants. Or, the hand of consolation, among his servants, through its effect. Above, ch. 27: there is no indignation in me. He also sets down the greatness of the punishment: for behold, the Lord — in fire, by which the city was to be burned, or by which the world was to be purged. Chariots — the army of the Chaldeans, in which God comes, as it were; or the Angels who will come with him to judgment. Psalm 96: fire shall go before him. Amos 9: they shall perish by the sword of God. He also sets down the multitude of those punished: they shall be multiplied. Above, ch. 34: for the victim of the Lord is in Bosra, and a great slaughter in the land of Edom. Second, he reproaches their guilt: who were sanctifying themselves, thinking to cleanse themselves from uncleanness by waters, or even by the sacrifices of idols, in the gardens, in which they worshipped idols, or gave themselves over to pleasure, after one, coupling with women after the manner of beasts. Or, behind the door — literally, the mouse, the dormouse, against the law, Leviticus 11. Above, ch. 65: they eat swine's flesh, and unclean broth. But I. Here he pursues the manner of the discernment as regards all in common: and first he proclaims the universal judgment: their works and thoughts — judging, as it were, for both together; I come, on the day of judgment. Or, the various kingdoms of your enemies, and destroying the wicked among you. They shall come, to Jerusalem after your return, or to judgment, or to the faith. Joel 3: behold, I will raise them up out of the place in which you sold them. Second, he sets down the summons: and I will set among them — that is, among the Jews who shall be with Zerubbabel and the other leaders — a sign, the edict of Cyrus, to the nations, to which the Jews had been scattered; to Lydia, those who hold the arrow, because they are good archers; my glory, which shall appear in your deliverance. Above, ch. 11: he shall lift up a sign among the nations. Or, he sets the sign of the cross among the apostles, that all may be turned to God, as it were preparing them for judgment. Third, he sets down the preparation of those who are to be judged: and first as to the good; second as to the wicked: and they shall go forth, and shall see. The first is in two parts. First, as to the Jews, setting down their honorable return: they shall bring them on horses — by which are signified the aids which those returning had from the Gentiles. Baruch 5: the Lord shall bring these to you. Or there are signified the various conditions of those who are converted to the faith, as the Gloss expounds. Second, the exaltation of their return, first as to dignity: and I will take — which was fulfilled literally in the Jews, and also in the apostles. Above, ch. 61: you shall be called the priests of the Lord; it shall be said of you, ministers of our God. Second, as to the preservation of their offspring: for as the new heavens, as above, ch. 65 — so shall it stand, forever. Jeremiah 31: if these laws shall fail before me, says the Lord, then the seed of Israel also shall fail. Or, the saints shall stand forever, renewed like heaven and earth. Third, as to the duration of their glory: and it shall be month — as though month shall succeed month, and feast shall succeed feast, in your prosperity. Above, ch. 29: year has been added to year, and the solemnities have run their course. Mystically, the Church after the end; spiritual rest after carnal. Second, as to the Gentiles: and all shall come — because from the various nations they came to Jerusalem to worship the Lord. Psalm 85: all the nations shall come and shall adore before you, O Lord. Or, on the day of judgment: and they shall go forth. Here he sets down the second judgment, as regards the wicked: and first the outflow of the punishment: and they shall go forth, coming to Jerusalem, and they shall see, in the ancient tombs, and in the fields, the bones of their dead fathers. Above, ch. 34: their slain shall be cast out, and from their carcasses a stench shall rise. Or, the saints shall see the damned falling into damnation. Second, he sets down the duration of the punishment: their worm — of conscience, by which even the dead shall be tormented; and fire — of hell. Judith 16: he will give fire and worms into their flesh. Third, the delight taken in these punishments, as regards those who see them: and they shall be unto satiety to all flesh — that is, to the saints. Psalm 57: the just shall rejoice when he shall see the revenge. From these punishments may he free us, who has granted both to begin and to complete. And thus ends the sentence and the literal exposition on Isaiah according to Brother Thomas Aquinas, which Brother Iacobinus of Asti, of the province of Lombardy, at that time a student in the general house of studies at Naples, transcribed into legible letters, completing the authorities. He also arranged collations at certain places upon each of the lectures, and this he did for the benefit of the friars of our order, and that copies of the said writings might be had. Therefore, praise be to him who granted both to begin and to complete. Amen.”

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“He that killeth an ox, is as if he slew a man,.... Not that killed the ox of his neighbour, which, according to law, he was to pay for; or that killed one for food, which was lawful to be done; but that slew one, and offered it as a sacrifice; not blamed because blind or lame, or had any blemish in it, and so unfit for sacrifice; or because not rightly offered, under a due sense of sin, and with repentance for it, and faith in Christ; but because all sacrifices of this kind are now abolished in Gospel times, to which this prophecy belongs; Christ the great sacrifice being offered up; and therefore to offer sacrifice, which, notwithstanding the unbelieving Jews continued daily, till it was made to cease by the destruction of their temple, was a great offence to God; it was as grievous to him as offering their children to Moloch; or as the murder of a man; and was indeed a trampling under foot the Son of God, and accounting his blood and sacrifice as nothing, which was highly displeasing to God: he that sacrificeth a lamb, as if he cut off a dog's neck; the lamb for the daily sacrifice, morning and evening, or the passover lamb, or any other: this now is no more acceptable to God, than if a dog, a very impure creature, was slain, his head cut off, and offered on the altar; which was so abominable to the Lord, that the price of one might not be brought into his house, Deu 23:18, he that offereth an oblation, as if he offered swine's blood; the meat offering, made of fine flour, on which oil was poured, and frankincense put, Lev 2:1, however rightly composed it might be, and offered according to law, yet now of no more esteem with God than blood, which was forbidden by the same law; nay, than the blood of swine, which creature itself, according to the ceremonial law, was unclean, and might not be eaten, and much less be offered up, and still less its blood, Lev 11:7, and he that burneth incense, as if he blessed an idol; or that "remembers incense" (p); that offers it as a memorial of mercies, and by way of thankfulness for them, as if he gave thanks to an idol, which is nothing, and vanity and vexation in the world; sacrifices of such kind, be they what they will, are reckoned no other than as idolatry and will worship: yea, they have chosen their own ways: which were evil, and opposite to the ways of God, especially to the way of salvation by Christ; they gave heed to the traditions of the elders; continued the service of the ceremonial law; and set up their own righteousness, in opposition to the doctrines, ordinances, sacrifice, and righteousness of Christ: and their soul delighteth in their abominations: things which were abominable unto God; as were their traditions, which were preferred to the word of God, and by which they made it void; and their sacrifices being offered up contrary to his will, and with a wicked mind; and their righteousness being imperfect, and trusted in, to the neglect and contempt of the righteousness of his Son. (p) , , Sept.; "qui recordatur thuris", V. L. Calvin, Vatablus; "memorans thus", Montanus.”
Source
1849
A.D.
1774–1849
“He. Septuagint, “the wicked who.” (Haydock) — Ox. This is a prophecy, that the sacrifices which were offered in the old law, should be abolished in the new; and that the offering of them should be a crime. (Challoner) — Without the proper dispositions, sacrifice only displeases God. (Calmet) — Brain, or slay. (Haydock) — Incense. To offer it in the way of a sacrifice; (Challoner) or to remind God of his people. The expression is popular, but energetic, Leviticus ii. 2, 9., and vi. 15. — Ways, to please themselves, and to bind me. But I will not have a divided heart, chap. i. 11., and lviii. 3. (Calmet)”
Source
1863
A.D.
1796–1863
“The sacrifice of an ox, under the Christian dispensation, is a crime, since God no longer wishes to be worshipped after this fashion. Under the Mosaic law persons offering sacrifice might incur the Divine anger on account of their perverse dispositions, so that the act of sacrifice might prove offensive to God, like the crime of murder.”
Source
“To kill a sheep with a view of offering it in sacrifice, is as offensive to God as if one should cut off the head of a dog ; which animal was rejected as unclean.”
“nniD. Flour and oil with incense. This oblation, which was prescribed in the law, is now offen- sive, like the pouring out of swine's blood as a libation. A pure offering is everywhere presented. Mai. 1 : 11.”
1871
A.D.
1871
“God loathes even the sacrifices of the wicked (Isa 1:11; Pro 15:8; Pro 28:9). is as if--LOWTH not so well omits these words: "He that killeth an ox (presently after) murders a man" (as in Eze 23:39). But the omission in the Hebrew of "is as if"--increases the force of the comparison. Human victims were often offered by the heathen. dog's neck--an abomination according to the Jewish law (Deu 23:18); perhaps made so, because dogs were venerated in Egypt. He does not honor this abomination by using the word "sacrifice," but uses the degrading term, "cut off a dog's neck" (Exo 13:13; Exo 34:20). Dogs as unclean are associated with swine (Mat 7:6; Pe2 2:22). oblation--unbloody: in antithesis to "swine's blood" (Isa 65:4). burneth--Hebrew, "he who offereth as a memorial oblation" (Lev 2:2). they have chosen--opposed to the two first clauses of Isa 66:4 : "as they have chosen their own ways, &c., so I will choose their delusions.”
Source
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.