The interpretation timeline
Jeremiah 2:21 Douay-Rheims

Yet I planted thee a chosen vineyard, all true seed: how then art thou turned unto me into that which is good for nothing, O strange vineyard?

A.D. 339 – 1871 10 witnesses 12 excerpts

Patristic

before A.D. 750
339
A.D.
c. A.D. 260–339
“So also God is introduced by the prophet as saying to the person who had become evil by his own choice, "Yet I had planted you a fruitful vine. How have you turned back into a wild vine?" Anywhere it is said that evils happen to the wicked from God, it must be understood as an accidental coincidence of name. This name is given to the chastisements that God in his goodness is said to send not for the hurt of those who are chastised but for their benefit and profit, in the same way that a physician might be thought to apply bad things in his painful and bitter remedies to save the sick.”
Source
386
A.D.
Cyril of Jerusalem Patristic
A.D. 313–386
“Sin is a terrible thing, and the most grievous disease of the soul is iniquity, which corrupts the fiber of the soul and makes it liable to eternal fire. It is an evil freely chosen, the product of the will. The prophet clearly declares that we sin of our own free will: "I had planted you, a choice vine of fully tested stock; how could you turn into bitterness, a spurious vine?" The planting was good, but the fruit coming from the will is evil. So the planter is blameless, but the vine will burn with fire since it was planted for good and bore evil fruit of its own will.”
Source
“Learn this also, that before the soul comes into the world, it has committed no sin. But though we came into the world sinless, we now of our own choice commit sin.… Remember also how God again accuses them and says, "I have planted you a choice vine, wholly of pure seed; how then have you turned degenerate and become a wild vine?"”
Source
397
A.D.
Ambrose of Milan Patristic
A.D. 339–397
“Yet if the husband's power allures you, pray tell me who it was that spoke in the prophet, saying, "O Lord, make it known to me that I may know. Then I saw their thoughts. I was led as a harmless lamb to the slaughter and knew it not. They took counsel together against me, saying, Come, let us throw wood into his bread." For if the Son here spoke of the mystery of his coming incarnation—because it was blasphemous to suppose that the words are spoken concerning the Father—then surely it is the Son who speaks in an earlier passage: "I have planted you as a fruitful vine—how did you become bitter, and a wild vine?"”
Source
407
A.D.
John Chrysostom Patristic
A.D. 347–407
“Hence God gave the gift of prayer. But he does this, even though he does not need for us to ask, but that we might not grow indifferent from being saved without effort. For this reason, he said to Jeremiah, "Do not pray for this people, for I will not hear you," not wishing to stop his praying (for he earnestly longs for our salvation) but to terrify them. Seeing this, the prophet did not stop praying. So that you may see that God did not wish to turn Jeremiah from it, but to shame them that he said this, hear what it says. "Don't you see what they are doing?" Also when he says to the city, "Although you wash yourself with soda and use an abundance of soap, the stain of your guilt is still before me," it is not that he may cast them into despair that he so speaks, but that he may rouse them to repentance.”
Source
430
A.D.
Augustine of Hippo Patristic
A.D. 354–430
“For it is by similitude, and not by any personal propriety, that He is thus called a vine; just as He is also termed a sheep, a lamb, a lion, a rock, a corner-stone, and other names of a like kind, which are themselves rather the true ones, from which these are drawn as similitudes, not as realities. But when He says, "I am the true vine," it is to distinguish Himself, doubtless, from that vine to which the words are addressed: "How art thou turned into sourness, as a strange vine?" For how could that be a true vine which was expected to bring forth grapes and brought forth thorns?”
Source
“All they that refuse Christ for King become strangers. Wherefore strangers are they made? Because even that vine, though by Him planted, when it had become sour what heard it? "Wherefore hast thou been turned into sourness, O alien vine?" It hath not been said, My vine: because if Mine, sweet; if sour, not Mine; if not Mine, surely alien.”
Source

Scholastic

c. 1100 – 1500
1105
A.D.
Rashi Jewish
1040–1105
“I planted you a noble vine stock Heb. שורק is the branches of a good vine, that is to say the children of pious and righteous fathers. Its midrashic interpretation is: I planted you שורק. I added for you to the seven commandments of the children of Noah, six hundred and six, as is the numerical value of שורק. degenerate Heb. סוּרי (Destoultours in O.F). wild vine that grows in the forests.”
Source
1252
A.D.
Thomas Aquinas Catholic
1225–1274
“Here he removes the excuse: and first, the excuse they might have had by alleging the negligence of the cultivator: against which, I planted you, a chosen one, from chosen fathers. Isa. 5: "A vineyard was made for my beloved on a horn, a son of oil," etc. Second, the excuse they might have had by denying guilt, at "if you wash yourself." And first he convicts them of guilt against God; second, of guilt against neighbor, at "why do you strive to show your way good?" Concerning the first, two points. First he convicts them of guilt, showing the impossibility of denial. Nitre, which, condensed by the heat of the sun, like salt, washes away filth; berith, a certain herb for washing away filth: and it is a manner of speaking, as if he were to say: all the water of the river would not make you clean, that is, there is no excuse or purgation for you. Prov. 30: "a generation that seems clean to itself, and yet is not washed from its filth." How do you say: I am not polluted? Prov. 20: "who can say: my heart is clean, I am pure from sin?" And he sets forth the purgation of guilt, proposing two circumstances. First, the place: see the ways, the works, in the valley, of the sons of Ennon, where they worshipped idols. This place is watered by the springs of Siloe, and there was the shrine of Baal, according to the Gloss. Below, 31: "direct your heart into the right way in which you walked." And he sets forth the manner of the sin as regards the eagerness for sinning. A swift runner, as one unencumbered for sinning. Prov. 1: "their feet run to evil, and they hasten to shed blood." As regards the fervor of concupiscence: a wild ass in desire, namely of coitus, drew in the wind, by which it perceives the scent of its female, the love of the thing loved. Below, 14: "wild asses stood on the rocks, they drew in the wind like dragons." As regards strong adherence, none shall turn her away, by removing her. And as regards the readiness for sinning, all who seek her: as if he were speaking of a harlot, who even at the time of her menses shows herself to her lovers. Ezech. 16: "you opened your feet to every one that passed by, and multiplied all your fornications." Second, he convicts them of hardness of mind: and first, because they are not called back by warnings; second, because they are not corrected by scourges, at "why do you wish to contend with me in judgment?" Third, because they are not bent by benefits, at "see the word of the Lord." Concerning the first, three points. First he sets forth the admonition, forbid: as if he were to say: cease from sins, for which, barefoot and thirsting, you are led into captivity, as Isa. 20: "as my servant Isaiah walked naked and unshod, so shall the king of the Assyrians lead away the captivity of Egypt, and the migration of Ethiopia, of young men and old, naked and unshod, with buttocks uncovered, to the shame of Egypt." Second, he shows the rebellion of the people: and you said, I have despaired, I will not do it. Strangers: idols. Below, 18: "they said: we have despaired, we will walk after our own thoughts, and each of us will do the wickedness of his evil heart." Third, he threatens confusion: and first he sets forth a likeness of the confusion: as a thief is confounded when he is caught, so they are confounded, caught in their punishments; wood: a wooden idol; father: God. Ps. 96: "let all be confounded who worship graven images, and who glory in their idols." Isa. 1: "they shall be confounded by their idols." Second, he expounds the order of the confusion, first setting forth the withdrawal of the divine help, they have turned, as being disobedient. Zach. 7: "they turned away the shoulder, withdrawing, and made their ears heavy, lest they should hear the law." In the time of affliction. Osee 6: "in their tribulation they will rise early to me." Come, and let us return to the Lord, etc. Second, he sets forth the uselessness of the idols. Where are the gods? Deut. 32: "where are their gods, in whom they have trust?" Third, the multitude of the idols: for according to the number of your cities were your gods, O Juda. Isa. 2: "his land is filled with horses, and his chariots are innumerable."”
Source

Post-Reformation

c. 1650 – 1900
1771
A.D.
John Gill Reformed
1697–1771
“For though thou wash thee with nitre,.... The word "nitre", is only used in this place and in Pro 25:20 and it is hard to say what it is. Kimchi and Ben Melech observe, that some say it is what is called "alum"; and others that it is a dust with which they wash the head, and cleanse everything; and so Jarchi says it is a kind of earth used in cleaning garments; and "nitre" is mentioned by the Misnic doctors (s) among those things which are used for the washing of garments, and taking spots out of them; though about what it is they are not agreed; and it seems the nitre of the ancients is unknown to us (t); and saltpetre is put in the room of it; and some render the word here "saltpetre"; and Pliny (u) observes, that nitre does not much differ from salt, and ascribes to it a virtue of eating out filth, and removing it; so Aristotle (w) reports of the lake Ascania; that its water is of such a nitrous quality, that garments, being put into it, need no other washing. Nitre has its name from "to loose", because it looses the filth, and cleanses from it: and take thee much soap. The Septuagint render it, "herb"; and the Vulgate Latin version, "the herb borith"; which is the Hebrew word here used; and about the sense of which there is some difficulty. Kimchi and Ben Melech say some take it to be the same with what is called "soap"; so Jarchi; and others, that it is an herb with which they wash, the same that is called fullers' herb; but whether it is soap, or fullers' herb, or fullers' earth, as others, it is certain it is something fullers used in cleaning garments, as appear from Mal 3:2, where the same word is used, and fullers made mention of as using what is signified by it. It has its name from which signifies to "cleanse" and "purify". The sense is, let this backsliding and degenerate people take what methods they will to cleanse themselves from their sins, as by their ceremonial ablutions and sacrifices, which was the usual method they had recourse to, to purify themselves, and in which they rested: yet thine iniquity is marked before me, saith the Lord God; or, "will retain its spots" (x) these remain; the filth is not washed away; the iniquity is not hid and covered; it appears very plain and manifest; yea, shines like gold; or, "is gilded" (y); as the word used signifies. It is of too deep a die to be removed by such external things; nothing but the blood of Christ can cleanse from sin, take away its filth, removes its guilt, and cover it out of the sight of God, so that it can be seen no more. The Targum is, "for if you think to be cleansed from your sins, as they cleanse with nitre, or make white with "borith", or soap; lo, as the mark of a spot which is not clean, so are your sins multiplied before me, saith the Lord God.'' (s) Misn. Sabbat, c. 9. sect. 5. & Nidda, c. 9. sect. 6. & Maimon & Bartenora in ib. & in Misn. Celim, c. 10. sect. 1. (t) Schroder. Pharmacopoeia, l. 3. c. 23. p. 140. (u) Nat. Hist. l. 31. c. 10. (w) Opera, vol. 1, de Mirabil. p. 705. (x) "Maculas tamen retinebit iniquitas tua", Schmidt. (y) "nitet, vel splendet, instar anri", Piscator; "obducat se auro insigni", Junius & Tremellius; so Gussetius renders the word, "inaurari, auro ebduci"; and who rightly observes, that whatever is glided, or covered with gold, the more it is washed with nitre, or soap, the brighter it will appear; and so, whatever other methods are taken to wash away sin, but seeking for justification by the grace of God in Christ, it will be but the more manifest, Ebr. Comment. p. 410.”
Source
1849
A.D.
1774–1849
“Chosen. Hebrew, Sorek, Judges xvi. 4., and Isaias v. 2., and xvi. 8. (Calmet) — God created all things good, planted his Church in justice, and no evil proceeds from Him. (Worthington)”
1871
A.D.
Modern · 1953 →

The in-app commentary runs from the Fathers to the early-modern record, then stops — that's where the public-domain sources end, not where the reading does. For the modern reading, follow the sources directly.